leflunomide has been researched along with Respiratory Distress Syndrome in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present the case of a 62-year-old man with rheumatoid arthritis who developed a leukaemoid reaction and acute respiratory distress syndrome (ARDS) following granulocyte colony-stimulating factor (G-CSF) administration that had been given to treat neutropenia secondary to methotrexate and leflunomide toxicity." | 4.12 | Acute respiratory distress syndrome precipitated by granulocyte colony-stimulating factor in undiagnosed ( Chua, C; Cooke, R; Doig, C; Leung, T, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doig, C | 1 |
| Cooke, R | 1 |
| Chua, C | 1 |
| Leung, T | 1 |
1 other study available for leflunomide and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Acute respiratory distress syndrome precipitated by granulocyte colony-stimulating factor in undiagnosed
Topics: Granulocyte Colony-Stimulating Factor; Humans; Leflunomide; Male; Methotrexate; Middle Aged; Neutrop | 2022 |