leflunomide has been researched along with Renal Insufficiency, Chronic in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "NC, with renal failure secondary to bilateral dysplastic kidneys, received an LRD renal transplant (tx) at 17 months of age." | 1.40 | Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child. ( Habib, S; Latiolais, LS; McClure, GB; Reisman, L; Vanchiere, JA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reisman, L | 1 |
| Habib, S | 1 |
| McClure, GB | 1 |
| Latiolais, LS | 1 |
| Vanchiere, JA | 1 |
| Gagneux-Brunon, A | 1 |
| Pillet, S | 1 |
| Laurent, B | 1 |
| Mariat, C | 1 |
| Michalet, M | 1 |
| Lucht, F | 1 |
| Botelho-Nevers, E | 1 |
2 other studies available for leflunomide and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child.
Topics: Administration, Oral; Biopsy; BK Virus; Child, Preschool; Ciprofloxacin; Creatinine; Cytosine; DNA, | 2014 |
A case of BK virus nephropathy in a stem cell transplant recipient: a rare or under-recognized cause for Acute Kidney injury.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; BK Virus; Ciprofloxacin; Cord Blood Stem Cell Transplant | 2015 |