leflunomide has been researched along with Pulmonary Sarcoidosis in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide has been reported as an alternative therapy in sarcoidosis." | 7.77 | Effectiveness and safety of leflunomide for pulmonary and extrapulmonary sarcoidosis. ( Bandyopadhyay, D; Chapman, JT; Culver, DA; Lazar, CA; Parambil, JG; Pearson, K; Sahoo, DH; Xu, M, 2011) |
| "Leflunomide has been reported as an alternative therapy in sarcoidosis." | 3.77 | Effectiveness and safety of leflunomide for pulmonary and extrapulmonary sarcoidosis. ( Bandyopadhyay, D; Chapman, JT; Culver, DA; Lazar, CA; Parambil, JG; Pearson, K; Sahoo, DH; Xu, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Au, S | 1 |
| Mirsaeidi, M | 1 |
| Aronson, IK | 1 |
| Sweiss, NJ | 2 |
| Sahoo, DH | 1 |
| Bandyopadhyay, D | 1 |
| Xu, M | 1 |
| Pearson, K | 1 |
| Parambil, JG | 1 |
| Lazar, CA | 1 |
| Chapman, JT | 1 |
| Culver, DA | 1 |
| Baughman, RP | 1 |
| Nunes, H | 1 |
| Lower, EE | 1 |
| Sugiyama, Y | 1 |
| Chida, K | 1 |
| Ogura, T | 1 |
| Yamaguchi, T | 1 |
| Miyazaki, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Endobronchial Mucosal Biopsy in Patients With Suspected Pulmonary Sarcoidosis[NCT04904939] | 20 participants (Actual) | Interventional | 2020-05-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for leflunomide and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Established and experimental medical therapy of pulmonary sarcoidosis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials | 2013 |
3 other studies available for leflunomide and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Adalimumab Induced Subcutaneous Nodular Sarcoidosis; A Rare Side Effect of Tumor Necrosis Factor-α Inhibitor.
Topics: Adalimumab; Biopsy; Female; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Middle Aged; | 2014 |
Effectiveness and safety of leflunomide for pulmonary and extrapulmonary sarcoidosis.
Topics: Adjuvants, Immunologic; Female; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Sarcoidosis; Sar | 2011 |
[Diagnosis of and therapy for diffuse lung diseases (discussion)].
Topics: Alveolitis, Extrinsic Allergic; Biomarkers; Bronchiolitis; Gefitinib; Humans; Isoxazoles; Leflunomid | 2006 |