leflunomide has been researched along with Postoperative Complications in 10 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Excerpt | Relevance | Reference |
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" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance." | 7.85 | Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017) |
"Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 5.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance." | 3.85 | Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017) |
"Leflunomide treatment for CMV disease in renal transplant recipients is effective, simple, and economical." | 2.71 | A prospective evaluation of leflunomide therapy for cytomegalovirus disease in renal transplant recipients. ( Balakrishnan, N; Chandy, S; Chandy, SJ; Fleming, DH; Jacob, CK; John, GT; Kirubakaran, MG; Krishnamurthy, K; Manivannan, J; Peter, S, 2005) |
" The dosage and time of therapy need to be explored in the future; additional studies of large samples are needed." | 1.42 | BK Virus-Associated Nephropathy with Plasma Cell-Rich Infiltrates Treated by Bortezomib-Based Regimen. ( Chen, JS; Cheng, DR; Ji, SM; Li, X; Liu, ZH; Wen, JQ; Wu, D; Xie, KN; Zhang, MC, 2015) |
"Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 1.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (10.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 4 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Echenique, IA | 1 |
Beltran, D | 1 |
Ramirez-Ruiz, L | 1 |
Najafian, N | 1 |
Agrawal, N | 1 |
Velázquez Benito, A | 1 |
Bellosta Diago, E | 1 |
Santos Lasaosa, S | 1 |
Pascual Millán, LF | 1 |
Wu, D | 1 |
Zhang, MC | 1 |
Chen, JS | 1 |
Li, X | 1 |
Cheng, DR | 1 |
Xie, KN | 1 |
Ji, SM | 1 |
Liu, ZH | 1 |
Wen, JQ | 1 |
Jung, YH | 1 |
Moon, KC | 1 |
Ha, JW | 1 |
Kim, SJ | 1 |
Ha, IS | 1 |
Cheong, HI | 1 |
Kang, HG | 1 |
John, GT | 1 |
Manivannan, J | 1 |
Chandy, S | 1 |
Peter, S | 1 |
Fleming, DH | 1 |
Chandy, SJ | 1 |
Balakrishnan, N | 1 |
Krishnamurthy, K | 1 |
Kirubakaran, MG | 1 |
Jacob, CK | 1 |
Josephson, MA | 1 |
Javaid, B | 1 |
Kadambi, PV | 1 |
Meehan, SM | 1 |
Williams, JW | 1 |
Fuerst, M | 1 |
Möhl, H | 1 |
Baumgärtel, K | 1 |
Rüther, W | 1 |
Duclos, AJ | 1 |
Krishnamurthi, V | 1 |
Lard, M | 1 |
Poggio, E | 1 |
Kleeman, M | 1 |
Winans, C | 1 |
Fatica, R | 1 |
Nurko, S | 1 |
Battiwalla, M | 1 |
Paplham, P | 1 |
Almyroudis, NG | 1 |
McCarthy, A | 1 |
Abdelhalim, A | 1 |
Elefante, A | 1 |
Smith, P | 1 |
Becker, J | 1 |
McCarthy, PL | 1 |
Segal, BH | 1 |
Gregory, CR | 1 |
3 reviews available for leflunomide and Postoperative Complications
Article | Year |
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Leflunomide therapy for BK virus allograft nephropathy after pediatric kidney transplantation.
Topics: Antiviral Agents; BK Virus; Child; Female; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantati | 2013 |
Leflunomide in solid organ transplantation and polyoma virus infection.
Topics: Antiviral Agents; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Organ Transplantation; | 2006 |
Immunosuppressive approaches to the prevention of graft vascular disease.
Topics: Coronary Disease; Cyclosporine; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase I | 1998 |
1 trial available for leflunomide and Postoperative Complications
Article | Year |
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A prospective evaluation of leflunomide therapy for cytomegalovirus disease in renal transplant recipients.
Topics: Adult; Antiviral Agents; Cytomegalovirus Infections; Female; Humans; Isoxazoles; Kidney Transplantat | 2005 |
6 other studies available for leflunomide and Postoperative Complications
Article | Year |
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Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Respo | 2017 |
[Acute sensory-motor axonal neuropathy (Guillain-Barre syndrome) following vertebroplasty].
Topics: Accidental Falls; Arthritis, Rheumatoid; Female; Guillain-Barre Syndrome; Humans; Immunocompromised | 2014 |
BK Virus-Associated Nephropathy with Plasma Cell-Rich Infiltrates Treated by Bortezomib-Based Regimen.
Topics: Adult; Antineoplastic Agents; BK Virus; Bortezomib; Female; Humans; Isoxazoles; Kidney Diseases; Kid | 2015 |
Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Thera | 2006 |
Prevalence and clinical course of BK virus nephropathy in pancreas after kidney transplant patients.
Topics: Antiviral Agents; BK Virus; Drug Therapy, Combination; Humans; Immunosuppression Therapy; Isoxazoles | 2006 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Co | 2007 |