leflunomide has been researched along with Polychondritis, Relapsing in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Polychondritis, Relapsing: An acquired disease of unknown etiology, chronic course, and tendency to recur. It is characterized by inflammation and degeneration of cartilage and can result in deformities such as floppy ear and saddle nose. Loss of cartilage in the respiratory tract can lead to respiratory obstruction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handler, RP | 1 |
| Koenig, AS | 1 |
| Abruzzo, JL | 1 |
2 other studies available for leflunomide and Polychondritis, Relapsing
| Article | Year |
|---|---|
Leflunomide for relapsing polychondritis: successful longterm treatment.
Topics: Anti-Inflammatory Agents; C-Reactive Protein; Cholestyramine Resin; Drug Therapy, Combination; Fever | 2006 |
Leflunomide induced fevers, thrombocytosis, and leukocytosis in a patient with relapsing polychondritis.
Topics: Anti-Inflammatory Agents; C-Reactive Protein; Cholestyramine Resin; Drug Therapy, Combination; Fever | 2002 |