Page last updated: 2024-10-30

leflunomide and Pleural Effusion

leflunomide has been researched along with Pleural Effusion in 2 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"We report the case of a young man, affected by rheumatoid arthritis who developed a rapid-onset short-of-breath, hemoptysis, and severe weakness, about 2 weeks after the administration of leflunomide."7.74Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis. ( Carloni, A; Giannakakis, K; Nori, G; Piciucchi, S; Poletti, V; Zobel, BB, 2008)
" A diagnosis of stage 2 sarcoidosis with pleural involvement was made and treatment with prednisone was started."3.75A 50-year-old man with stage 2 sarcoidosis with pleural involvement. ( Arrossi, A; Modrykamien, A; Reddy, A, 2009)
"We report the case of a young man, affected by rheumatoid arthritis who developed a rapid-onset short-of-breath, hemoptysis, and severe weakness, about 2 weeks after the administration of leflunomide."3.74Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis. ( Carloni, A; Giannakakis, K; Nori, G; Piciucchi, S; Poletti, V; Zobel, BB, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Modrykamien, A1
Arrossi, A1
Reddy, A1
Carloni, A1
Piciucchi, S1
Giannakakis, K1
Nori, G1
Zobel, BB1
Poletti, V1

Other Studies

2 other studies available for leflunomide and Pleural Effusion

ArticleYear
A 50-year-old man with stage 2 sarcoidosis with pleural involvement.
    Journal of hospital medicine, 2009, Volume: 4, Issue:4

    Topics: Antirheumatic Agents; Dyspnea; Humans; Isoxazoles; Leflunomide; Lung; Male; Middle Aged; Pleural Dis

2009
Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis.
    Journal of thoracic imaging, 2008, Volume: 23, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Diagnosis, Differenti

2008