leflunomide has been researched along with Peste-des-Petits-Ruminants in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Peste-des-Petits-Ruminants: A highly fatal contagious disease of goats and sheep caused by PESTE-DES-PETITS-RUMINANTS VIRUS. The disease may be acute or subacute and is characterized by stomatitis, conjunctivitis, diarrhea, and pneumonia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, L | 1 |
| Li, Y | 1 |
| Pu, F | 1 |
| Wang, H | 1 |
| Zhang, D | 1 |
| Bai, J | 1 |
| Shang, Y | 1 |
| Ma, Z | 1 |
| Ma, XX | 1 |
1 other study available for leflunomide and Peste-des-Petits-Ruminants
| Article | Year |
|---|---|
Inhibiting pyrimidine biosynthesis impairs Peste des Petits Ruminants Virus replication through depletion of nucleoside pools and activation of cellular immunity.
Topics: Animals; Antiviral Agents; Biphenyl Compounds; Enzyme Inhibitors; HEK293 Cells; Humans; Immunity, Ce | 2021 |