leflunomide and Pancreatic Neoplasms
leflunomide has been researched along with Pancreatic Neoplasms in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"A high incidence of pancreatic cancer (PCa) in patients exposed to was observed in the German biologics register." | 1.37 | Detection and evaluation of a drug safety signal concerning pancreatic cancer: lessons from a joint approach of three European biologics registers. ( Arkema, E; Askling, J; Davies, R; Hyrich, K; Listing, J; Neovius, M; Simard, J; Strangfeld, A; Symmons, D; Watson, K; Zink, A, 2011) |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Yu, M | 1 |
Nguyen, ND | 1 |
Huang, Y | 1 |
Lin, D | 1 |
Fujimoto, TN | 1 |
Molkentine, JM | 1 |
Deorukhkar, A | 1 |
Kang, Y | 1 |
San Lucas, FA | 1 |
Fernandes, CJ | 1 |
Koay, EJ | 1 |
Gupta, S | 1 |
Ying, H | 1 |
Koong, AC | 1 |
Herman, JM | 1 |
Fleming, JB | 1 |
Maitra, A | 1 |
Taniguchi, CM | 1 |
Strangfeld, A | 1 |
Hyrich, K | 1 |
Askling, J | 1 |
Arkema, E | 1 |
Davies, R | 1 |
Listing, J | 1 |
Neovius, M | 1 |
Simard, J | 1 |
Symmons, D | 1 |
Watson, K | 1 |
Zink, A | 1 |
Other Studies
2 other studies available for leflunomide and Pancreatic Neoplasms
Article | Year |
---|---|
Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer.
Topics: Animals; Carcinoma, Pancreatic Ductal; CRISPR-Cas Systems; Disease Models, Animal; Dynamins; Enzyme | 2019 |
Detection and evaluation of a drug safety signal concerning pancreatic cancer: lessons from a joint approach of three European biologics registers.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Biomarkers; Cohort St | 2011 |