leflunomide has been researched along with Osteomalacia in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Osteomalacia: Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rickets and osteomalacia are metabolic bone diseases due to a mineralization defect as principal pathophysiology." | 2.43 | [Adverse events in rheumatoid arthritis patient with etanercept therapy: the appearance of osteomalacia]. ( D'Amore, M; D'Amore, S; Minenna, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Amore, M | 1 |
| Minenna, G | 1 |
| D'Amore, S | 1 |
1 review available for leflunomide and Osteomalacia
| Article | Year |
|---|---|
[Adverse events in rheumatoid arthritis patient with etanercept therapy: the appearance of osteomalacia].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Etanercept; Fe | 2005 |