Page last updated: 2024-10-30

leflunomide and Opportunistic Infections

leflunomide has been researched along with Opportunistic Infections in 8 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.

Research Excerpts

ExcerptRelevanceReference
" The dosage of mycophenolate sodium was tapered from 720 to 360 mg daily and that of everolimus increased from 0."1.51Successful Treatment for BK Virus Nephropathy by Leflunomide in a Kidney Transplant Patient: A Case Report. ( Chen, HA; Chen, YW; Hsu, YH; Hung, LY; Lee, CH; Wu, MS; Wu, MY, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morel, J1
Constantin, A1
Baron, G1
Dernis, E1
Flipo, RM1
Rist, S1
Combe, B1
Gottenberg, JE1
Schaeverbeke, T1
Soubrier, M1
Vittecoq, O1
Dougados, M1
Saraux, A1
Mariette, X1
Ravaud, P1
Sibilia, J1
Wu, MY1
Chen, YW1
Hung, LY1
Lee, CH1
Chen, HA1
Hsu, YH1
Wu, MS1
Jaw, J1
Hill, P1
Goodman, D1
Orden, AO1
Chuluyan, JC1
Colombini, AC1
Barbera, RF1
Butts, RJ1
Uber, WE1
Savage, AJ1
Hocevar, A1
Rozman, B1
Praprotnik, S1
Lestan, B1
Erzen, D1
Petric, V1
Tomsic, M1
Grover, R1
Dhir, V1
Aneja, R1
Arya, V1
Galle, A1
Marwaha, V1
Kumar, A1
Bruyn, GA1
Jansen, TL1
Ten Brinke, A1
De Vries, M1
Houtman, PM1
van Roon, EN1

Other Studies

8 other studies available for leflunomide and Opportunistic Infections

ArticleYear
Risk factors of serious infections in patients with rheumatoid arthritis treated with tocilizumab in the French Registry REGATE.
    Rheumatology (Oxford, England), 2017, 10-01, Volume: 56, Issue:10

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Autoant

2017
Successful Treatment for BK Virus Nephropathy by Leflunomide in a Kidney Transplant Patient: A Case Report.
    Transplantation proceedings, 2019, Volume: 51, Issue:5

    Topics: BK Virus; Everolimus; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Trans

2019
Combination of Leflunomide and Everolimus for treatment of BK virus nephropathy.
    Nephrology (Carlton, Vic.), 2017, Volume: 22, Issue:4

    Topics: Aged; BK Virus; Drug Substitution; Drug Therapy, Combination; Everolimus; Female; Graft Rejection; G

2017
Leflunomide use in a cytomegalovirus infection of a patient with dermatomyositis.
    Rheumatology international, 2012, Volume: 32, Issue:1

    Topics: Antirheumatic Agents; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Dermatomyositis

2012
Treatment of BK viremia in a pediatric heart transplant recipient.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012, Volume: 31, Issue:5

    Topics: Antiviral Agents; BK Virus; Child; Female; Graft Rejection; Heart Transplantation; Humans; Immunosup

2012
Leflunomide-associated tuberculosis?
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Immunos

2006
Severe infections following leflunomide therapy for rheumatoid arthritis.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:7

    Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mid

2006
Cavitating pneumonia, a severe complication of leflunomide therapy in chronic polyarthritis.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Female; Humans; Isoxazoles; Leflunomide; Male; Middle

2007