leflunomide has been researched along with Nerve Pain in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Even ongoing inflammatory edema and mechanical allodynia were reduced by leflunomide." | 1.48 | Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1. ( Augusto, PSA; Brito, AMS; Coelho, MM; Costa, SOAM; Dutra, MGMB; Godin, AM; Goulart, FA; Ísis Morais, M; Machado, RR; Melo, ISF; Menezes, RR; Rodrigues, FF, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brito, AMS | 1 |
| Godin, AM | 1 |
| Augusto, PSA | 1 |
| Menezes, RR | 1 |
| Melo, ISF | 1 |
| Dutra, MGMB | 1 |
| Costa, SOAM | 1 |
| Goulart, FA | 1 |
| Rodrigues, FF | 1 |
| Ísis Morais, M | 1 |
| Machado, RR | 1 |
| Coelho, MM | 1 |
1 other study available for leflunomide and Nerve Pain
| Article | Year |
|---|---|
Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1.
Topics: Animals; Chemokine CXCL1; Glyburide; Hyperalgesia; Isoxazoles; Leflunomide; Male; Mice; Naltrexone; | 2018 |