Page last updated: 2024-10-30

leflunomide and Nephrosis

leflunomide has been researched along with Nephrosis in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

Research Excerpts

ExcerptRelevanceReference
" This study aims to evaluate the effect of leflunomide on HSPN adults with nephrotic proteinuria."7.80Leflunomide in addition to steroids improves proteinuria and renal function in adult Henoch-Schoenlein nephritis with nephrotic proteinuria. ( Gao, Y; He, H; Liu, G; Liu, L; Zhang, Y; Zhang, Z, 2014)
" This study aims to evaluate the effect of leflunomide on HSPN adults with nephrotic proteinuria."3.80Leflunomide in addition to steroids improves proteinuria and renal function in adult Henoch-Schoenlein nephritis with nephrotic proteinuria. ( Gao, Y; He, H; Liu, G; Liu, L; Zhang, Y; Zhang, Z, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Y1
Gao, Y1
Zhang, Z1
Liu, G1
He, H1
Liu, L1

Other Studies

1 other study available for leflunomide and Nephrosis

ArticleYear
Leflunomide in addition to steroids improves proteinuria and renal function in adult Henoch-Schoenlein nephritis with nephrotic proteinuria.
    Nephrology (Carlton, Vic.), 2014, Volume: 19, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Female; Humans; IgA Vasculitis; Isoxazoles; Kidney; Leflunomid

2014