Page last updated: 2024-10-30

leflunomide and Nephritis

leflunomide has been researched along with Nephritis in 5 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Nephritis: Inflammation of any part of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
" We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis."8.89Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013)
" A previous study reported that leflunomide (LEF) with a corticosteroid was effective for adult patients with HSPN and nephrotic proteinuria."8.02Leflunomide therapy for IgA vasculitis with nephritis in children. ( Du, Y; Hou, L; Zhang, Z, 2021)
" We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis."4.89Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013)
" A previous study reported that leflunomide (LEF) with a corticosteroid was effective for adult patients with HSPN and nephrotic proteinuria."4.02Leflunomide therapy for IgA vasculitis with nephritis in children. ( Du, Y; Hou, L; Zhang, Z, 2021)
"BK viremia and nephritis are increasing problems in renal transplant recipients."2.43BK virus nephritis after renal transplantation. ( Hariharan, S, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hou, L1
Zhang, Z1
Du, Y1
Yang, D1
Keys, B1
J Conti, D1
Foulke, L1
Stellrecht, K1
Cook, L1
Lopez-Soler, RI1
Canivet, C1
Rostaing, L1
Galvani, S1
Böhler, T1
Gandia, P1
Mengelle, C1
Guilbeau-Frugier, C1
Thomsen, M1
Salvayre, R1
Negre-Salvayre, A1
Kamar, N1
Pinto, B1
Dhir, V1
Krishnan, S1
Nada, R1
Hariharan, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288]0 participants (Actual)Observational2015-09-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for leflunomide and Nephritis

ArticleYear
JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:2

    Topics: Biopsy; BK Virus; Creatinine; Graft Rejection; Humans; Immunoglobulins, Intravenous; Immunosuppressi

2017
Leflunomide-induced DRESS syndrome with renal involvement and vasculitis.
    Clinical rheumatology, 2013, Volume: 32, Issue:5

    Topics: Antirheumatic Agents; Biopsy; Drug Hypersensitivity Syndrome; Eosinophilia; Erythema; Exanthema; Hum

2013
BK virus nephritis after renal transplantation.
    Kidney international, 2006, Volume: 69, Issue:4

    Topics: Antibodies, Viral; Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Graft Survival; Huma

2006

Other Studies

2 other studies available for leflunomide and Nephritis

ArticleYear
Leflunomide therapy for IgA vasculitis with nephritis in children.
    BMC pediatrics, 2021, 09-08, Volume: 21, Issue:1

    Topics: Adult; Child; Humans; IgA Vasculitis; Immunoglobulin A; Leflunomide; Nephritis; Proteinuria

2021
Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome.
    International immunopharmacology, 2009, Volume: 9, Issue:9

    Topics: Adult; Aged; Antigens, CD; BK Virus; Cell Proliferation; Disease Progression; Female; Follow-Up Stud

2009