leflunomide has been researched along with Nephritis in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Nephritis: Inflammation of any part of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis." | 8.89 | Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013) |
| " A previous study reported that leflunomide (LEF) with a corticosteroid was effective for adult patients with HSPN and nephrotic proteinuria." | 8.02 | Leflunomide therapy for IgA vasculitis with nephritis in children. ( Du, Y; Hou, L; Zhang, Z, 2021) |
| " We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis." | 4.89 | Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013) |
| " A previous study reported that leflunomide (LEF) with a corticosteroid was effective for adult patients with HSPN and nephrotic proteinuria." | 4.02 | Leflunomide therapy for IgA vasculitis with nephritis in children. ( Du, Y; Hou, L; Zhang, Z, 2021) |
| "BK viremia and nephritis are increasing problems in renal transplant recipients." | 2.43 | BK virus nephritis after renal transplantation. ( Hariharan, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, L | 1 |
| Zhang, Z | 1 |
| Du, Y | 1 |
| Yang, D | 1 |
| Keys, B | 1 |
| J Conti, D | 1 |
| Foulke, L | 1 |
| Stellrecht, K | 1 |
| Cook, L | 1 |
| Lopez-Soler, RI | 1 |
| Canivet, C | 1 |
| Rostaing, L | 1 |
| Galvani, S | 1 |
| Böhler, T | 1 |
| Gandia, P | 1 |
| Mengelle, C | 1 |
| Guilbeau-Frugier, C | 1 |
| Thomsen, M | 1 |
| Salvayre, R | 1 |
| Negre-Salvayre, A | 1 |
| Kamar, N | 1 |
| Pinto, B | 1 |
| Dhir, V | 1 |
| Krishnan, S | 1 |
| Nada, R | 1 |
| Hariharan, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288] | 0 participants (Actual) | Observational | 2015-09-30 | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for leflunomide and Nephritis
| Article | Year |
|---|---|
JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.
Topics: Biopsy; BK Virus; Creatinine; Graft Rejection; Humans; Immunoglobulins, Intravenous; Immunosuppressi | 2017 |
Leflunomide-induced DRESS syndrome with renal involvement and vasculitis.
Topics: Antirheumatic Agents; Biopsy; Drug Hypersensitivity Syndrome; Eosinophilia; Erythema; Exanthema; Hum | 2013 |
BK virus nephritis after renal transplantation.
Topics: Antibodies, Viral; Antiviral Agents; BK Virus; Cidofovir; Cytosine; DNA, Viral; Graft Survival; Huma | 2006 |
2 other studies available for leflunomide and Nephritis
| Article | Year |
|---|---|
Leflunomide therapy for IgA vasculitis with nephritis in children.
Topics: Adult; Child; Humans; IgA Vasculitis; Immunoglobulin A; Leflunomide; Nephritis; Proteinuria | 2021 |
Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome.
Topics: Adult; Aged; Antigens, CD; BK Virus; Cell Proliferation; Disease Progression; Female; Follow-Up Stud | 2009 |