Page last updated: 2024-10-30

leflunomide and Nail Diseases

leflunomide has been researched along with Nail Diseases in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Nail Diseases: Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.

Research Excerpts

ExcerptRelevanceReference
"Prominent nail changes in lichenoid drug eruptions, particularly in children, are rare but should be considered in children with new-onset nail dystrophy."1.46Lichenoid Drug Eruption with Prominent Nail Changes Due to Leflunomide in a 12-Year-Old Child. ( Brandling-Bennett, HA; Cole, B; Fleckman, P; May, C; Sidbury, R, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
May, C1
Fleckman, P1
Brandling-Bennett, HA1
Cole, B1
Sidbury, R1

Other Studies

1 other study available for leflunomide and Nail Diseases

ArticleYear
Lichenoid Drug Eruption with Prominent Nail Changes Due to Leflunomide in a 12-Year-Old Child.
    Pediatric dermatology, 2017, Volume: 34, Issue:4

    Topics: Antirheumatic Agents; Child; Drug Eruptions; Female; Humans; Isoxazoles; Leflunomide; Lichenoid Erup

2017