Page last updated: 2024-10-30

leflunomide and Myocarditis

leflunomide has been researched along with Myocarditis in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dimitrijevic, M1
Milenkovic, M1
Milosavljevic, P1
Colic, M1

Other Studies

1 other study available for leflunomide and Myocarditis

ArticleYear
Effects of leflunomide on experimental autoimmune myocarditis with special reference to the dendritic cells.
    Transplantation proceedings, 1998, Volume: 30, Issue:8

    Topics: Animals; Autoimmune Diseases; Dendritic Cells; Freund's Adjuvant; Heart; Immunosuppressive Agents; I

1998