leflunomide has been researched along with Mitochondrial Diseases in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xuan, J | 1 |
| Ren, Z | 1 |
| Qing, T | 1 |
| Couch, L | 1 |
| Shi, L | 1 |
| Tolleson, WH | 1 |
| Guo, L | 1 |
1 other study available for leflunomide and Mitochondrial Diseases
| Article | Year |
|---|---|
Mitochondrial dysfunction induced by leflunomide and its active metabolite.
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Bongkrekic Acid; Chemical and Drug | 2018 |