leflunomide has been researched along with Meningitis, Aseptic in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Meningitis, Aseptic: A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report the first known case of leflunomide-induced aseptic meningitis, in a patient with rheumatoid arthritis." | 7.72 | Leflunomide-induced aseptic meningitis. ( Cohen, JD; Jorgensen, C; Sany, J, 2004) |
| " We report the first known case of leflunomide-induced aseptic meningitis, in a patient with rheumatoid arthritis." | 3.72 | Leflunomide-induced aseptic meningitis. ( Cohen, JD; Jorgensen, C; Sany, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mäder, L | 1 |
| Kollmar, R | 1 |
| Lorenz, HM | 1 |
| Cohen, JD | 1 |
| Jorgensen, C | 1 |
| Sany, J | 1 |
2 other studies available for leflunomide and Meningitis, Aseptic
| Article | Year |
|---|---|
Leflunomide as Cause of Aseptic Meningitis.
Topics: Humans; Leflunomide; Meningitis, Aseptic | 2021 |
Leflunomide-induced aseptic meningitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Isoxazoles; Leflunomide; Mal | 2004 |