Page last updated: 2024-10-30

leflunomide and MODS

leflunomide has been researched along with MODS in 2 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"Wistar albino type rats were randomly divided into five groups: control, sham, leflunomide, sepsis, and sepsis + leflunomide."7.80Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis. ( Fadillioglu, E; Karaman, A; Ozturk, E; Samdancı, E; Surucu, M, 2014)
"Wistar albino type rats were randomly divided into five groups: control, sham, leflunomide, sepsis, and sepsis + leflunomide."3.80Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis. ( Fadillioglu, E; Karaman, A; Ozturk, E; Samdancı, E; Surucu, M, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ozturk, E1
Surucu, M1
Karaman, A1
Samdancı, E1
Fadillioglu, E1
Miszewska-Szyszkowska, D1
Mikołajczyk, N1
Komuda-Leszek, E1
Wieczorek-Godlewska, R1
Świder, R1
Dęborska-Materkowska, D1
Szmidt, J1
Durlik, M1

Other Studies

2 other studies available for leflunomide and MODS

ArticleYear
Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis.
    The Journal of surgical research, 2014, Volume: 187, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Catalase; Cecum; Disease

2014
Severe cytomegalovirus infection in a second kidney transplant recipient treated with ganciclovir, leflunomide, and immunoglobulins, with complications including seizures, acute HCV infection, drug-induced pancytopenia, diabetes, cholangitis, and multi-or
    Annals of transplantation, 2015, Mar-27, Volume: 20

    Topics: Adult; Antiviral Agents; Cholangitis; Cytomegalovirus Infections; Diabetes Mellitus, Type 2; Fatal O

2015