leflunomide has been researched along with Lung Neoplasms in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Currently, SU101 in combination with cytotoxic agents is in late-stage clinical development for the treatment of cancers." | 1.31 | Effects of SU101 in combination with cytotoxic agents on the growth of subcutaneous tumor xenografts. ( Cherrington, JM; Kabbinavar, F; Mann, E; Schwartz, DP; Shawver, LK; Slamon, DJ; Strawn, LM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, M | 1 |
| Ponce-Aix, S | 1 |
| Navarro, A | 1 |
| Riera-Knorrenschild, J | 1 |
| Schmidt, M | 1 |
| Wiegert, E | 1 |
| Kapp, K | 1 |
| Wittig, B | 1 |
| Mauri, C | 1 |
| Dómine Gómez, M | 1 |
| Kollmeier, J | 1 |
| Sadjadian, P | 1 |
| Fröhling, KP | 1 |
| Huber, RM | 1 |
| Wolf, M | 1 |
| Strawn, LM | 1 |
| Kabbinavar, F | 1 |
| Schwartz, DP | 1 |
| Mann, E | 1 |
| Shawver, LK | 1 |
| Slamon, DJ | 1 |
| Cherrington, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Clinical Study of Maintenance Therapy With Immunomodulator MGN1703 in Patients With Extensive Disease Small Cell Lung Cancer After Platinum-Based First-Line Therapy[NCT02200081] | Phase 2 | 103 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for leflunomide and Lung Neoplasms
| Article | Year |
|---|---|
Immunotherapeutic maintenance treatment with toll-like receptor 9 agonist lefitolimod in patients with extensive-stage small-cell lung cancer: results from the exploratory, controlled, randomized, international phase II IMPULSE study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cohort Studies; Etoposide; F | 2018 |
1 other study available for leflunomide and Lung Neoplasms
| Article | Year |
|---|---|
Effects of SU101 in combination with cytotoxic agents on the growth of subcutaneous tumor xenografts.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Div | 2000 |