leflunomide has been researched along with Liver Failure in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avery, RK | 1 |
| Bolwell, BJ | 1 |
| Yen-Lieberman, B | 1 |
| Lurain, N | 1 |
| Waldman, WJ | 1 |
| Longworth, DL | 1 |
| Taege, AJ | 1 |
| Mossad, SB | 1 |
| Kohn, D | 1 |
| Long, JR | 1 |
| Curtis, J | 1 |
| Kalaycio, M | 1 |
| Pohlman, B | 1 |
| Williams, JW | 1 |
| Thomasset, SC | 1 |
| Ong, SL | 1 |
| Large, SR | 1 |
2 other studies available for leflunomide and Liver Failure
| Article | Year |
|---|---|
Use of leflunomide in an allogeneic bone marrow transplant recipient with refractory cytomegalovirus infection.
Topics: Bone Marrow Transplantation; Cytomegalovirus Infections; Drug Resistance, Viral; Drug Therapy, Combi | 2004 |
Post-coronary artery bypass graft liver failure: a possible association with leflunomide.
Topics: Aged; Arthritis, Rheumatoid; Coronary Artery Bypass; Fatal Outcome; Female; Gastrointestinal Hemorrh | 2005 |