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leflunomide and B-Cell Chronic Lymphocytic Leukemia

leflunomide has been researched along with B-Cell Chronic Lymphocytic Leukemia in 3 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"Treatment with leflunomide reduced serum viral titres and stabilized renal function."1.38Native kidney BK virus nephropathy associated with chronic lymphocytic leukaemia. ( Gray, M; Leonard, N; McCrory, R; Smyth, J; Woodman, A, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dietrich, S1
Krämer, OH1
Hahn, E1
Schäfer, C1
Giese, T1
Hess, M1
Tretter, T1
Rieger, M1
Hüllein, J1
Zenz, T1
Ho, AD1
Dreger, P1
Luft, T1
McCrory, R1
Gray, M1
Leonard, N1
Smyth, J1
Woodman, A1
Ringshausen, I1
Oelsner, M1
Bogner, C1
Peschel, C1
Decker, T1

Other Studies

3 other studies available for leflunomide and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Leflunomide induces apoptosis in fludarabine-resistant and clinically refractory CLL cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-15, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Aniline Compounds; Antineoplastic Agents; Apoptosis; CD40 Ligand; Cell Prol

2012
Native kidney BK virus nephropathy associated with chronic lymphocytic leukaemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:3

    Topics: Aged; BK Virus; DNA, Viral; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Leflunomi

2012
The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells.
    Leukemia, 2008, Volume: 22, Issue:3

    Topics: Apoptosis; B-Lymphocytes; Crotonates; Cyclin A; Cyclin D3; Cyclin-Dependent Kinase 2; Cyclins; Dihyd

2008
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