leflunomide and B-Cell Chronic Lymphocytic Leukemia
leflunomide has been researched along with B-Cell Chronic Lymphocytic Leukemia in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Treatment with leflunomide reduced serum viral titres and stabilized renal function." | 1.38 | Native kidney BK virus nephropathy associated with chronic lymphocytic leukaemia. ( Gray, M; Leonard, N; McCrory, R; Smyth, J; Woodman, A, 2012) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Dietrich, S | 1 |
Krämer, OH | 1 |
Hahn, E | 1 |
Schäfer, C | 1 |
Giese, T | 1 |
Hess, M | 1 |
Tretter, T | 1 |
Rieger, M | 1 |
Hüllein, J | 1 |
Zenz, T | 1 |
Ho, AD | 1 |
Dreger, P | 1 |
Luft, T | 1 |
McCrory, R | 1 |
Gray, M | 1 |
Leonard, N | 1 |
Smyth, J | 1 |
Woodman, A | 1 |
Ringshausen, I | 1 |
Oelsner, M | 1 |
Bogner, C | 1 |
Peschel, C | 1 |
Decker, T | 1 |
Other Studies
3 other studies available for leflunomide and B-Cell Chronic Lymphocytic Leukemia
Article | Year |
---|---|
Leflunomide induces apoptosis in fludarabine-resistant and clinically refractory CLL cells.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Antineoplastic Agents; Apoptosis; CD40 Ligand; Cell Prol | 2012 |
Native kidney BK virus nephropathy associated with chronic lymphocytic leukaemia.
Topics: Aged; BK Virus; DNA, Viral; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Leflunomi | 2012 |
The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells.
Topics: Apoptosis; B-Lymphocytes; Crotonates; Cyclin A; Cyclin D3; Cyclin-Dependent Kinase 2; Cyclins; Dihyd | 2008 |