Page last updated: 2024-10-30

leflunomide and Leg Ulcer

leflunomide has been researched along with Leg Ulcer in 2 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"We report the case of a leg ulcer in a rheumatoid arthritis (RA) patient under treatment with leflunomide, discuss the influence of the drug on the aetiopathogenesis of the ulcer and describe its successful treatment."7.73Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy. ( Dissemond, J; Goos, M; Knab, J, 2005)
"We report the case of a leg ulcer in a rheumatoid arthritis (RA) patient under treatment with leflunomide, discuss the influence of the drug on the aetiopathogenesis of the ulcer and describe its successful treatment."3.73Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy. ( Dissemond, J; Goos, M; Knab, J, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seitz, CS1
Berens, N1
Bröcker, EB1
Trautmann, A1
Knab, J1
Goos, M1
Dissemond, J1

Reviews

1 review available for leflunomide and Leg Ulcer

ArticleYear
Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature.
    Dermatology (Basel, Switzerland), 2010, Volume: 220, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Rheumatoid; Etoricoxib; Female; Gram-Posi

2010

Other Studies

1 other study available for leflunomide and Leg Ulcer

ArticleYear
Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2005, Volume: 19, Issue:2

    Topics: Aged; Arthritis, Rheumatoid; Cholestyramine Resin; Debridement; Female; Humans; Immunosuppressive Ag

2005