leflunomide has been researched along with Leg Ulcer in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of a leg ulcer in a rheumatoid arthritis (RA) patient under treatment with leflunomide, discuss the influence of the drug on the aetiopathogenesis of the ulcer and describe its successful treatment." | 7.73 | Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy. ( Dissemond, J; Goos, M; Knab, J, 2005) |
| "We report the case of a leg ulcer in a rheumatoid arthritis (RA) patient under treatment with leflunomide, discuss the influence of the drug on the aetiopathogenesis of the ulcer and describe its successful treatment." | 3.73 | Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy. ( Dissemond, J; Goos, M; Knab, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seitz, CS | 1 |
| Berens, N | 1 |
| Bröcker, EB | 1 |
| Trautmann, A | 1 |
| Knab, J | 1 |
| Goos, M | 1 |
| Dissemond, J | 1 |
1 review available for leflunomide and Leg Ulcer
| Article | Year |
|---|---|
Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Rheumatoid; Etoricoxib; Female; Gram-Posi | 2010 |
1 other study available for leflunomide and Leg Ulcer
| Article | Year |
|---|---|
Successful treatment of a leg ulcer occurring in a rheumatoid arthritis patient under leflunomide therapy.
Topics: Aged; Arthritis, Rheumatoid; Cholestyramine Resin; Debridement; Female; Humans; Immunosuppressive Ag | 2005 |