leflunomide has been researched along with Keratoacanthoma in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 78-year-old woman diagnosed with rheumatoid arthritis without a history of skin tumors or immunosuppressive medication, started treatment with leflunomide." | 7.79 | Multiple eruptive keratoacanthomas associated with leflunomide. ( Bouret, AM; Frances, L; Guijarro, J; Leiva-Salinas, Mdel C; Marin, I, 2013) |
| "A 78-year-old woman diagnosed with rheumatoid arthritis without a history of skin tumors or immunosuppressive medication, started treatment with leflunomide." | 3.79 | Multiple eruptive keratoacanthomas associated with leflunomide. ( Bouret, AM; Frances, L; Guijarro, J; Leiva-Salinas, Mdel C; Marin, I, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frances, L | 1 |
| Guijarro, J | 1 |
| Marin, I | 1 |
| Leiva-Salinas, Mdel C | 1 |
| Bouret, AM | 1 |
| Tidwell, WJ | 1 |
| Malone, J | 1 |
| Callen, JP | 1 |
| Schmutz, JL | 1 |
3 other studies available for leflunomide and Keratoacanthoma
| Article | Year |
|---|---|
Multiple eruptive keratoacanthomas associated with leflunomide.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carcinoma, Squamous Cell; Drug | 2013 |
Eruptive Keratoacanthomas Associated With Leflunomide.
Topics: Antirheumatic Agents; Drug Eruptions; Female; Humans; Isoxazoles; Keratoacanthoma; Leflunomide; Midd | 2016 |
[Eruptive keratoacanthomas and leflunomide].
Topics: Antirheumatic Agents; Drug Eruptions; Humans; Immunocompromised Host; Isoxazoles; Keratoacanthoma; L | 2016 |