Page last updated: 2024-10-30

leflunomide and Keratoacanthoma

leflunomide has been researched along with Keratoacanthoma in 3 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.

Research Excerpts

ExcerptRelevanceReference
"A 78-year-old woman diagnosed with rheumatoid arthritis without a history of skin tumors or immunosuppressive medication, started treatment with leflunomide."7.79Multiple eruptive keratoacanthomas associated with leflunomide. ( Bouret, AM; Frances, L; Guijarro, J; Leiva-Salinas, Mdel C; Marin, I, 2013)
"A 78-year-old woman diagnosed with rheumatoid arthritis without a history of skin tumors or immunosuppressive medication, started treatment with leflunomide."3.79Multiple eruptive keratoacanthomas associated with leflunomide. ( Bouret, AM; Frances, L; Guijarro, J; Leiva-Salinas, Mdel C; Marin, I, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frances, L1
Guijarro, J1
Marin, I1
Leiva-Salinas, Mdel C1
Bouret, AM1
Tidwell, WJ1
Malone, J1
Callen, JP1
Schmutz, JL1

Other Studies

3 other studies available for leflunomide and Keratoacanthoma

ArticleYear
Multiple eruptive keratoacanthomas associated with leflunomide.
    Dermatology online journal, 2013, Jul-14, Volume: 19, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carcinoma, Squamous Cell; Drug

2013
Eruptive Keratoacanthomas Associated With Leflunomide.
    JAMA dermatology, 2016, Volume: 152, Issue:1

    Topics: Antirheumatic Agents; Drug Eruptions; Female; Humans; Isoxazoles; Keratoacanthoma; Leflunomide; Midd

2016
[Eruptive keratoacanthomas and leflunomide].
    Annales de dermatologie et de venereologie, 2016, Volume: 143, Issue:4

    Topics: Antirheumatic Agents; Drug Eruptions; Humans; Immunocompromised Host; Isoxazoles; Keratoacanthoma; L

2016