leflunomide has been researched along with Joint Pain in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the clinical efficacy and safety of Huayu Tongbi Recipe (HTR) combined methotrexate (MTX) in treating refractory rheumatoid arthritis (RRA)." | 9.20 | [Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate]. ( Chen, XM; Chu, YL; Huang, QC; Huang, RY; Liu, ZH; Yan, JY, 2015) |
| "To evaluate the clinical efficacy and safety of Huayu Tongbi Recipe (HTR) combined methotrexate (MTX) in treating refractory rheumatoid arthritis (RRA)." | 5.20 | [Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate]. ( Chen, XM; Chu, YL; Huang, QC; Huang, RY; Liu, ZH; Yan, JY, 2015) |
| "Two cases of leflunomide-induced peripheral neuropathy are described; in a 60-year-old woman with sero-negative polyarthralgia-myalgia syndrome and a 65-year-old man with sero-negative rheumatoid arthritis, both treated with leflunomide at 20mg/day." | 3.74 | Leflunomide-induced peripheral neuropathy. ( Kermode, AG; Kho, LK, 2007) |
| "Leflunomide is a long-term treatment option for patients with predominantly joint disease." | 1.32 | [Psoriasis arthritis--long-term treatment of two patients with leflunomide]. ( Schmitt, J; Wozel, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wig, S | 1 |
| McCabe, PS | 1 |
| Swamy, S | 1 |
| Sultan, J | 1 |
| Vasireddy, S | 1 |
| Chen, XM | 1 |
| Huang, RY | 1 |
| Yan, JY | 1 |
| Liu, ZH | 1 |
| Chu, YL | 1 |
| Huang, QC | 1 |
| Schmitt, J | 1 |
| Wozel, G | 1 |
| Kho, LK | 1 |
| Kermode, AG | 1 |
| Pchelintseva, AO | 1 |
| Korotaeva, TV | 1 |
| Godzenko, AA | 1 |
| Korsakova, IuL | 1 |
| Stanislav, ML | 1 |
| Denisov, LN | 1 |
2 trials available for leflunomide and Joint Pain
| Article | Year |
|---|---|
[Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate].
Topics: Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Drug Therapy, Combination; Drugs, Chinese H | 2015 |
[Results of leflunomide treatment of psoriatic arthritis].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Arthralgia; Arthritis, Psoriatic; Dose-Response Rel | 2007 |
3 other studies available for leflunomide and Joint Pain
| Article | Year |
|---|---|
Pyomyositis: an unusual cause of hip pain in a patient on certolizumab pegol and leflunomide.
Topics: Aged; Antirheumatic Agents; Arthralgia; Certolizumab Pegol; Diagnosis, Differential; Drug Therapy, C | 2018 |
[Psoriasis arthritis--long-term treatment of two patients with leflunomide].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Psoriatic; Female; Humans; Is | 2004 |
Leflunomide-induced peripheral neuropathy.
Topics: Adjuvants, Immunologic; Aged; Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Female; Human | 2007 |