Page last updated: 2024-10-30

leflunomide and Joint Pain

leflunomide has been researched along with Joint Pain in 5 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the clinical efficacy and safety of Huayu Tongbi Recipe (HTR) combined methotrexate (MTX) in treating refractory rheumatoid arthritis (RRA)."9.20[Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate]. ( Chen, XM; Chu, YL; Huang, QC; Huang, RY; Liu, ZH; Yan, JY, 2015)
"To evaluate the clinical efficacy and safety of Huayu Tongbi Recipe (HTR) combined methotrexate (MTX) in treating refractory rheumatoid arthritis (RRA)."5.20[Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate]. ( Chen, XM; Chu, YL; Huang, QC; Huang, RY; Liu, ZH; Yan, JY, 2015)
"Two cases of leflunomide-induced peripheral neuropathy are described; in a 60-year-old woman with sero-negative polyarthralgia-myalgia syndrome and a 65-year-old man with sero-negative rheumatoid arthritis, both treated with leflunomide at 20mg/day."3.74Leflunomide-induced peripheral neuropathy. ( Kermode, AG; Kho, LK, 2007)
"Leflunomide is a long-term treatment option for patients with predominantly joint disease."1.32[Psoriasis arthritis--long-term treatment of two patients with leflunomide]. ( Schmitt, J; Wozel, G, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wig, S1
McCabe, PS1
Swamy, S1
Sultan, J1
Vasireddy, S1
Chen, XM1
Huang, RY1
Yan, JY1
Liu, ZH1
Chu, YL1
Huang, QC1
Schmitt, J1
Wozel, G1
Kho, LK1
Kermode, AG1
Pchelintseva, AO1
Korotaeva, TV1
Godzenko, AA1
Korsakova, IuL1
Stanislav, ML1
Denisov, LN1

Trials

2 trials available for leflunomide and Joint Pain

ArticleYear
[Treatment of Refractory Rheumatoid Arthritis by Huayu Tongbi Recipe Combined Methotrexate].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:11

    Topics: Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Drug Therapy, Combination; Drugs, Chinese H

2015
[Results of leflunomide treatment of psoriatic arthritis].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:8

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Arthralgia; Arthritis, Psoriatic; Dose-Response Rel

2007

Other Studies

3 other studies available for leflunomide and Joint Pain

ArticleYear
Pyomyositis: an unusual cause of hip pain in a patient on certolizumab pegol and leflunomide.
    Rheumatology (Oxford, England), 2018, 09-01, Volume: 57, Issue:9

    Topics: Aged; Antirheumatic Agents; Arthralgia; Certolizumab Pegol; Diagnosis, Differential; Drug Therapy, C

2018
[Psoriasis arthritis--long-term treatment of two patients with leflunomide].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2004, Volume: 2, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Psoriatic; Female; Humans; Is

2004
Leflunomide-induced peripheral neuropathy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2007, Volume: 14, Issue:2

    Topics: Adjuvants, Immunologic; Aged; Antirheumatic Agents; Arthralgia; Arthritis, Rheumatoid; Female; Human

2007