leflunomide has been researched along with Jaundice in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is a novel disease modifying antirheumatic drug (DMARD)." | 1.32 | Leflunomide for the treatment of rheumatoid arthritis in clinical practice: incidence and severity of hepatotoxicity. ( Brouwers, JR; Houtman, NM; Jansen, TL; Spoelstra, P; van Roon, EN, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Roon, EN | 1 |
| Jansen, TL | 1 |
| Houtman, NM | 1 |
| Spoelstra, P | 1 |
| Brouwers, JR | 1 |
1 other study available for leflunomide and Jaundice
| Article | Year |
|---|---|
Leflunomide for the treatment of rheumatoid arthritis in clinical practice: incidence and severity of hepatotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Female | 2004 |