Page last updated: 2024-10-30

leflunomide and Influenza, Human

leflunomide has been researched along with Influenza, Human in 1 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Influenza, Human: An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.

Research Excerpts

ExcerptRelevanceReference
" Leflunomide is an anti-inflammatory drug primarily used for treating rheumatoid arthritis (RA)."7.96A77 1726, the active metabolite of the anti-rheumatoid arthritis drug leflunomide, inhibits influenza A virus replication in vitro and in vivo by inhibiting the activity of Janus kinases. ( Hu, J; Liu, X; Peng, D; Prinz, RA; Sun, J; Wang, C; Wang, J; Xu, X, 2020)
" Leflunomide is an anti-inflammatory drug primarily used for treating rheumatoid arthritis (RA)."3.96A77 1726, the active metabolite of the anti-rheumatoid arthritis drug leflunomide, inhibits influenza A virus replication in vitro and in vivo by inhibiting the activity of Janus kinases. ( Hu, J; Liu, X; Peng, D; Prinz, RA; Sun, J; Wang, C; Wang, J; Xu, X, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Wang, J1
Sun, J1
Hu, J1
Wang, C1
Prinz, RA1
Peng, D1
Liu, X1
Xu, X1

Other Studies

1 other study available for leflunomide and Influenza, Human

ArticleYear
A77 1726, the active metabolite of the anti-rheumatoid arthritis drug leflunomide, inhibits influenza A virus replication in vitro and in vivo by inhibiting the activity of Janus kinases.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:8

    Topics: A549 Cells; Aniline Compounds; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line; Cell

2020