leflunomide has been researched along with Infection, Postoperative Wound in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The highest risk of infection is associated with corticosteroids depending on the dose, so that a dosage as low as possible but stable in the perioperative period is recommended." | 2.55 | [Perioperative management of immunosuppressive treatment in patients undergoing joint surgery]. ( Krüger, K, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krüger, K | 1 |
| Fuerst, M | 1 |
| Möhl, H | 1 |
| Baumgärtel, K | 1 |
| Rüther, W | 1 |
| Glück, T | 1 |
| Müller-Ladner, U | 1 |
2 reviews available for leflunomide and Infection, Postoperative Wound
| Article | Year |
|---|---|
[Perioperative management of immunosuppressive treatment in patients undergoing joint surgery].
Topics: Adrenal Cortex Hormones; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Arthroplasty, R | 2017 |
[Do DMARDs contibute to impaired healing after surgery? Should they be discontinued before surgery?].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Azathioprine; Biological Pro | 2007 |
1 other study available for leflunomide and Infection, Postoperative Wound
| Article | Year |
|---|---|
Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Thera | 2006 |