leflunomide has been researched along with Hypertrophy, Left Ventricular in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, ZG | 1 |
| Zhang, X | 1 |
| Yuan, YP | 1 |
| Jin, YG | 1 |
| Li, N | 1 |
| Kong, CY | 1 |
| Song, P | 1 |
| Tang, QZ | 1 |
| Daïen, CI | 1 |
| Fesler, P | 1 |
| du Cailar, G | 1 |
| Daïen, V | 1 |
| Mura, T | 1 |
| Dupuy, AM | 1 |
| Cristol, JP | 1 |
| Ribstein, J | 1 |
| Combe, B | 1 |
| Morel, J | 1 |
1 trial available for leflunomide and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Etanercept normalises left ventricular mass in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Echocardiography; Etanerce | 2013 |
1 other study available for leflunomide and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
A77 1726 (leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice.
Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Heart | 2018 |