leflunomide has been researched along with Hypertension, Pulmonary in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide, a disease-modifying antirheumatic drug, has been shown to be effective in the management of rheumatoid arthritis (RA)." | 7.78 | Leflunomide-induced pulmonary hypertension in a young woman with rheumatoid arthritis: a case report. ( Alvarez, PA; Blanco, MV; Flagel, S; Mazzocchi, O; Saad, AK, 2012) |
| " We report four cases of patients who developed PAH following a treatment by leflunomide for rheumatoid arthritis, psoriatic arthritis or undetermined connective tissue disease." | 3.88 | Pulmonary arterial hypertension in four patients treated by leflunomide. ( Chabanne, C; Coiffier, G; Coirier, V; Fournet, M; Jégo, P; Jouneau, S; Lescoat, A; Polard, E, 2018) |
| "Leflunomide, a disease-modifying antirheumatic drug, has been shown to be effective in the management of rheumatoid arthritis (RA)." | 3.78 | Leflunomide-induced pulmonary hypertension in a young woman with rheumatoid arthritis: a case report. ( Alvarez, PA; Blanco, MV; Flagel, S; Mazzocchi, O; Saad, AK, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lacoste-Palasset, T | 1 |
| Chaumais, MC | 1 |
| Weatherald, J | 1 |
| Savale, L | 1 |
| Jaïs, X | 1 |
| Price, LC | 1 |
| Khouri, C | 1 |
| Bulifon, S | 1 |
| Seferian, A | 1 |
| Jevnikar, M | 1 |
| Boucly, A | 1 |
| Manaud, G | 1 |
| Pancic, S | 1 |
| Chabanne, C | 2 |
| Ahmad, K | 1 |
| Volpato, M | 1 |
| Favrolt, N | 1 |
| Guillaumot, A | 1 |
| Horeau-Langlard, D | 1 |
| Prévot, G | 1 |
| Fesler, P | 1 |
| Bertoletti, L | 1 |
| Reynaud-Gaubert, M | 1 |
| Lamblin, N | 1 |
| Launay, D | 1 |
| Simonneau, G | 1 |
| Sitbon, O | 1 |
| Perros, F | 1 |
| Humbert, M | 1 |
| Montani, D | 1 |
| Coirier, V | 1 |
| Lescoat, A | 1 |
| Fournet, M | 1 |
| Coiffier, G | 1 |
| Jouneau, S | 1 |
| Polard, E | 1 |
| Jégo, P | 1 |
| Alvarez, PA | 1 |
| Saad, AK | 1 |
| Flagel, S | 1 |
| Mazzocchi, O | 1 |
| Blanco, MV | 1 |
| Martinez-Taboada, VM | 1 |
| Rodriguez-Valverde, V | 1 |
| Gonzalez-Vilchez, F | 1 |
| Armijo, JA | 1 |
4 other studies available for leflunomide and Hypertension, Pulmonary
| Article | Year |
|---|---|
Association between Leflunomide and Pulmonary Hypertension.
Topics: Cardiac Catheterization; Endothelial Cells; Humans; Hypertension, Pulmonary; Leflunomide; Lung; Phar | 2021 |
Pulmonary arterial hypertension in four patients treated by leflunomide.
Topics: Arthritis, Rheumatoid; Female; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Leflunomid | 2018 |
Leflunomide-induced pulmonary hypertension in a young woman with rheumatoid arthritis: a case report.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Hypertension, Pulmonary; Isoxazo | 2012 |
Pulmonary hypertension in a patient with rheumatoid arthritis treated with leflunomide.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Hypertension, Pulmonary; Isoxazol | 2004 |