leflunomide has been researched along with Herpes Zoster in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Herpes Zoster: An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare infectious risk between leflunomide versus TNF inhibitors (TNFi), and between tacrolimus versus TNFi among rheumatoid arthritis (RA) patients receiving methotrexate (MTX)." | 8.12 | Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study. ( Ha, YJ; Kang, EH; Lee, EB; Lee, JH; Lee, YJ; Shin, A, 2022) |
| "Patients with rheumatoid arthritis (RA) are at increased risk of herpes zoster (HZ), and the risk appears to be increased in patients treated with tofacitinib." | 7.85 | Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy. ( Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K, 2017) |
| "To compare infectious risk between leflunomide versus TNF inhibitors (TNFi), and between tacrolimus versus TNFi among rheumatoid arthritis (RA) patients receiving methotrexate (MTX)." | 4.12 | Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study. ( Ha, YJ; Kang, EH; Lee, EB; Lee, JH; Lee, YJ; Shin, A, 2022) |
| "Patients with rheumatoid arthritis (RA) are at increased risk of herpes zoster (HZ), and the risk appears to be increased in patients treated with tofacitinib." | 3.85 | Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy. ( Bananis, E; Chen, C; Curtis, JR; Fan, H; Hirose, T; Lindsey, S; Mendelsohn, AM; Nduaka, CI; Tanaka, Y; Valdez, H; Wang, L; Winthrop, KL; Yamaoka, K, 2017) |
| "Of these 22 patients, 16 had varicella and 6 had herpes zoster." | 1.43 | Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression. ( Aeschlimann, F; Baer, W; Berthet, G; Cannizzaro, E; Heininger, U; Hofer, M; Kaiser, D; Leuvenink, R; Schroeder, S; Woerner, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, A | 1 |
| Lee, JH | 1 |
| Ha, YJ | 1 |
| Lee, YJ | 1 |
| Lee, EB | 1 |
| Kang, EH | 1 |
| Winthrop, KL | 1 |
| Curtis, JR | 1 |
| Lindsey, S | 1 |
| Tanaka, Y | 1 |
| Yamaoka, K | 1 |
| Valdez, H | 1 |
| Hirose, T | 1 |
| Nduaka, CI | 1 |
| Wang, L | 1 |
| Mendelsohn, AM | 1 |
| Fan, H | 1 |
| Chen, C | 1 |
| Bananis, E | 1 |
| Zisman, D | 1 |
| Bitterman, H | 1 |
| Shalom, G | 1 |
| Feldhamer, I | 1 |
| Comanesther, D | 1 |
| Batat, E | 1 |
| Greenberg-Dotan, S | 1 |
| Cohen, S | 1 |
| Cohen, AD | 1 |
| Leuvenink, R | 1 |
| Aeschlimann, F | 1 |
| Baer, W | 1 |
| Berthet, G | 1 |
| Cannizzaro, E | 1 |
| Hofer, M | 1 |
| Kaiser, D | 1 |
| Schroeder, S | 1 |
| Heininger, U | 1 |
| Woerner, A | 1 |
| Liao, TL | 1 |
| Chen, YM | 1 |
| Liu, HJ | 1 |
| Chen, DY | 1 |
5 other studies available for leflunomide and Herpes Zoster
| Article | Year |
|---|---|
Infectious risk of add-on leflunomide or tacrolimus versus TNF inhibitors among patients with rheumatoid arthritis receiving background methotrexate: A population-based cohort study.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Herpes Zoster; Humans; Infections; Lefl | 2022 |
Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Dat | 2017 |
Psoriatic arthritis treatment and the risk of herpes zoster.
Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Azathioprine; Cyclosporine; Dru | 2016 |
Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression.
Topics: Acyclovir; Adolescent; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Chickenpox; Chil | 2016 |
Risk and severity of herpes zoster in patients with rheumatoid arthritis receiving different immunosuppressive medications: a case-control study in Asia.
Topics: Abatacept; Adalimumab; Adrenal Cortex Hormones; Adult; Aged; Antibodies, Monoclonal; Antibodies, Mon | 2017 |