leflunomide has been researched along with Hemoptysis in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Hemoptysis: Expectoration or spitting of blood originating from any part of the RESPIRATORY TRACT, usually from hemorrhage in the lung parenchyma (PULMONARY ALVEOLI) and the BRONCHIAL ARTERIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of a young man, affected by rheumatoid arthritis who developed a rapid-onset short-of-breath, hemoptysis, and severe weakness, about 2 weeks after the administration of leflunomide." | 7.74 | Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis. ( Carloni, A; Giannakakis, K; Nori, G; Piciucchi, S; Poletti, V; Zobel, BB, 2008) |
| "We report the case of a young man, affected by rheumatoid arthritis who developed a rapid-onset short-of-breath, hemoptysis, and severe weakness, about 2 weeks after the administration of leflunomide." | 3.74 | Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis. ( Carloni, A; Giannakakis, K; Nori, G; Piciucchi, S; Poletti, V; Zobel, BB, 2008) |
| "LEF at a dosage of 30 mg/day appears to be effective in the prevention of major relapses in WG, however, this is associated with an increased frequency of adverse events." | 2.73 | Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis. ( de Groot, K; Gross, WL; Hellmich, B; Iking-Konert, C; Manger, K; Metzler, C; Miehle, N; Reinhold-Keller, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Sun, L | 1 |
| Tan, W | 1 |
| Metzler, C | 1 |
| Miehle, N | 1 |
| Manger, K | 1 |
| Iking-Konert, C | 1 |
| de Groot, K | 1 |
| Hellmich, B | 1 |
| Gross, WL | 1 |
| Reinhold-Keller, E | 1 |
| Carloni, A | 1 |
| Piciucchi, S | 1 |
| Giannakakis, K | 1 |
| Nori, G | 1 |
| Zobel, BB | 1 |
| Poletti, V | 1 |
1 trial available for leflunomide and Hemoptysis
| Article | Year |
|---|---|
Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis.
Topics: Administration, Oral; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; C-Reactive Protein; Cyclo | 2007 |
2 other studies available for leflunomide and Hemoptysis
| Article | Year |
|---|---|
Clinical features of children with pulmonary microscopic polyangiitis: report of 9 cases.
Topics: Adolescent; Anemia; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Child; Child, | 2015 |
Diffuse alveolar hemorrhage after leflunomide therapy in a patient with rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Diagnosis, Differenti | 2008 |