leflunomide and Hematologic Diseases studies

leflunomide and Hematologic Diseases

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

Excerpt	Relevance	Reference
"Episcleritis and scleritis are relatively rare ocular diseases, which are commonly associated with rheumatic diseases including systemic lupus erythematosus (SLE)."	1.43	[Clinical characteristics of 4 cases of scleritis associated with systemic lupus erythematosus]. ( Jia, Y; Miao, H; Wang, L; Yang, Y; Zhang, XY; Zhou, YS, 2016)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	2 (50.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (50.00)

29.6817

2010's

2 (50.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Wang, L	1
Yang, Y	1
Jia, Y	1
Miao, H	1
Zhou, YS	1
Zhang, XY	1
Suzuki, Y	2
Sugii, S	1
Saito, E	1
Wakabayashi, T	1
Suwa, A	1

Studies

Wang, L

Yang, Y

Jia, Y

Miao, H

Zhou, YS

Zhang, XY

Suzuki, Y

Sugii, S

Saito, E

Wakabayashi, T

Suwa, A

Reviews

2 reviews available for leflunomide and Hematologic Diseases

Article	Year
[Adverse effects of DMARDs in treatment of rheumatoid arthritis]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Hematologic Diseases; H	2005
[Adverse effects of conventional DMARDs and biologic DMARDs]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug	2007

Article

Year

[Adverse effects of DMARDs in treatment of rheumatoid arthritis].

Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Hematologic Diseases; H

2005

[Adverse effects of conventional DMARDs and biologic DMARDs].

Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug

2007

Other Studies

2 other studies available for leflunomide and Hematologic Diseases

Article	Year
[Clinical characteristics of 4 cases of scleritis associated with systemic lupus erythematosus]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, 12-18, Volume: 48, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinucle	2016
[Anti-rheumatic drugs]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6 Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazol	2012

Article

Year

[Clinical characteristics of 4 cases of scleritis associated with systemic lupus erythematosus].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, 12-18, Volume: 48, Issue:6

Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinucle

2016

[Anti-rheumatic drugs].

Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazol

2012