leflunomide has been researched along with Glioma in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shawver, LK | 1 |
| Schwartz, DP | 1 |
| Mann, E | 1 |
| Chen, H | 1 |
| Tsai, J | 1 |
| Chu, L | 1 |
| Taylorson, L | 1 |
| Longhi, M | 1 |
| Meredith, S | 1 |
| Germain, L | 1 |
| Jacobs, JS | 1 |
| Tang, C | 1 |
| Ullrich, A | 1 |
| Berens, ME | 1 |
| Hersh, E | 1 |
| McMahon, G | 1 |
| Hirth, KP | 1 |
| Powell, TJ | 1 |
| Xu, X | 1 |
| Shen, J | 1 |
| Mall, JW | 1 |
| Myers, JA | 1 |
| Huang, W | 1 |
| Blinder, L | 1 |
| Saclarides, TJ | 1 |
| Williams, JW | 1 |
| Chong, AS | 1 |
2 other studies available for leflunomide and Glioma
| Article | Year |
|---|---|
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
Topics: 3T3 Cells; Animals; Brain Neoplasms; Cell Survival; Epidermal Growth Factor; Female; Glioma; Growth | 1997 |
In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action.
Topics: 3T3 Cells; Adjuvants, Immunologic; Aniline Compounds; Animals; Antineoplastic Agents; Carcinoma, Squ | 1999 |