leflunomide has been researched along with Forestier-Certonciny Syndrome in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A man (age: 76 years) on prednisone and leflunomide for polymyalgia rheumatica developed spontaneous severe haematomas." | 3.76 | [Rituximab in the treatment of acquired haemophilia A in a patient with polymyalgia rheumatica]. ( Braunert, L; Bruegel, M; Niederwieser, D; Pfrepper, C; Thiery, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamantopoulos, AP | 1 |
| Hetland, H | 1 |
| Myklebust, G | 1 |
| Braunert, L | 1 |
| Bruegel, M | 1 |
| Pfrepper, C | 1 |
| Thiery, J | 1 |
| Niederwieser, D | 1 |
| Adizie, T | 1 |
| Christidis, D | 1 |
| Dharmapaliah, C | 1 |
| Borg, F | 1 |
| Dasgupta, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter Randomized Placebo Controlled Treatment Study of Leflunomide in Polymyalgia Rheumatica[NCT03576794] | Phase 3 | 94 participants (Anticipated) | Interventional | 2019-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for leflunomide and Forestier-Certonciny Syndrome
| Article | Year |
|---|---|
Leflunomide as a corticosteroid-sparing agent in giant cell arteritis and polymyalgia rheumatica: a case series.
Topics: Adrenal Cortex Hormones; Aged; Female; Giant Cell Arteritis; Giant Cells; Humans; Isoxazoles; Leflun | 2013 |
[Rituximab in the treatment of acquired haemophilia A in a patient with polymyalgia rheumatica].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Murine-Derived; Cyclophospham | 2010 |
Efficacy and tolerability of leflunomide in difficult-to-treat polymyalgia rheumatica and giant cell arteritis: a case series.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Case-Control Studies; Female; Giant Cell Arteritis; H | 2012 |