leflunomide has been researched along with Fibromuscular Dysplasia in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Fibromuscular Dysplasia: An idiopathic, segmental, nonatheromatous disease of the musculature of arterial walls, leading to STENOSIS of small and medium-sized arteries. There is true proliferation of SMOOTH MUSCLE CELLS and fibrous tissue. Fibromuscular dysplasia lesions are smooth stenosis and occur most often in the renal and carotid arteries. They may also occur in other peripheral arteries of the extremity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Though cerebral vasospasm is one of the most serious complications of subarachnoid haemorrhage (SAH), its complex pathogenesis is poorly understood and available clinical treatment options are unsatisfactory." | 1.34 | Leflunomide prevents vasospasm secondary to subarachnoid haemorrhage. ( Belen, D; Besalti, O; Bolay, H; Kösemehmetoğlu, K; Simşek, S; Yiğitkanli, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belen, D | 1 |
| Besalti, O | 1 |
| Yiğitkanli, K | 1 |
| Kösemehmetoğlu, K | 1 |
| Simşek, S | 1 |
| Bolay, H | 1 |
1 other study available for leflunomide and Fibromuscular Dysplasia
| Article | Year |
|---|---|
Leflunomide prevents vasospasm secondary to subarachnoid haemorrhage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Basilar Artery; Disease Models, Animal; Fibromuscu | 2007 |