leflunomide has been researched along with Fetal Growth Retardation in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Fetal Growth Retardation: Failure of a FETUS to attain expected GROWTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is a drug used in rheumatoid arthritis with teratogenic and fetotoxic effects." | 1.35 | A pair of twins born after maternal exposure to leflunomide. ( Heine, K; Poets, CF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammad, I | 1 |
| Porter, TF | 1 |
| Heine, K | 1 |
| Poets, CF | 1 |
1 review available for leflunomide and Fetal Growth Retardation
| Article | Year |
|---|---|
An Update on Biologic Agents During Pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humani | 2020 |
1 other study available for leflunomide and Fetal Growth Retardation
| Article | Year |
|---|---|
A pair of twins born after maternal exposure to leflunomide.
Topics: Adult; Antirheumatic Agents; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Isoxazoles; | 2008 |