Page last updated: 2024-10-30

leflunomide and Exanthem

leflunomide has been researched along with Exanthem in 2 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
" We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis."8.89Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013)
" We report an unusual case of DRESS syndrome due to Leflunomide, also complicated by renal involvement in the form of granulomatous interstitial nephritis and vasculitis."4.89Leflunomide-induced DRESS syndrome with renal involvement and vasculitis. ( Dhir, V; Krishnan, S; Nada, R; Pinto, B, 2013)
"Four months later widespread prunosus skin rash appeared on her skin."1.35Severe cutaneous adverse drug reaction to leflunomide: a report of two cases. ( Guo, G; Jian, X; Li, X; Lin, D; Ruan, Y, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pinto, B1
Dhir, V1
Krishnan, S1
Nada, R1
Jian, X1
Guo, G1
Ruan, Y1
Lin, D1
Li, X1

Reviews

1 review available for leflunomide and Exanthem

ArticleYear
Leflunomide-induced DRESS syndrome with renal involvement and vasculitis.
    Clinical rheumatology, 2013, Volume: 32, Issue:5

    Topics: Antirheumatic Agents; Biopsy; Drug Hypersensitivity Syndrome; Eosinophilia; Erythema; Exanthema; Hum

2013

Other Studies

1 other study available for leflunomide and Exanthem

ArticleYear
Severe cutaneous adverse drug reaction to leflunomide: a report of two cases.
    Cutaneous and ocular toxicology, 2008, Volume: 27, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents; Blister; Drug Eruptions; Exanthema; Female; Glucocorticoids; H

2008