leflunomide has been researched along with Erythema Multiforme in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Erythema Multiforme: A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic bull's-eye lesions usually occurring on the dorsal aspect of the hands and forearms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is an immunosuppressive agent that acts by inhibiting pyrimidine synthesis in lymphocytes and other rapidly proliferating cells, as well as by suppressing tumor necrosis factor-alpha-induced cellular responses." | 5.35 | Leflunomide-induced subacute cutaneous lupus erythematosus with erythema multiforme-like lesions. ( Alessi, E; Barbareschi, M; Del Papa, N; Marzano, AV; Ramoni, S, 2008) |
| "Leflunomide is an antirheumatic agent of the type of a 'disease-modifying antirheumatic drug'." | 5.32 | Erythema multiforme-like drug eruption with oral involvement after intake of leflunomide. ( Barta, U; Bauer, HI; Elsner, P; Fischer, TW; Graefe, T, 2003) |
| "Leflunomide is an immunosuppressive agent that acts by inhibiting pyrimidine synthesis in lymphocytes and other rapidly proliferating cells, as well as by suppressing tumor necrosis factor-alpha-induced cellular responses." | 1.35 | Leflunomide-induced subacute cutaneous lupus erythematosus with erythema multiforme-like lesions. ( Alessi, E; Barbareschi, M; Del Papa, N; Marzano, AV; Ramoni, S, 2008) |
| "Leflunomide is an antirheumatic agent of the type of a 'disease-modifying antirheumatic drug'." | 1.32 | Erythema multiforme-like drug eruption with oral involvement after intake of leflunomide. ( Barta, U; Bauer, HI; Elsner, P; Fischer, TW; Graefe, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, YQ | 1 |
| Mu, ZL | 1 |
| Zhang, JZ | 1 |
| Fischer, TW | 1 |
| Bauer, HI | 1 |
| Graefe, T | 1 |
| Barta, U | 1 |
| Elsner, P | 1 |
| Suess, A | 1 |
| Sticherling, M | 1 |
| Marzano, AV | 1 |
| Ramoni, S | 1 |
| Del Papa, N | 1 |
| Barbareschi, M | 1 |
| Alessi, E | 1 |
4 other studies available for leflunomide and Erythema Multiforme
| Article | Year |
|---|---|
Erythema multiforme-like drug eruption in a patient with systemic lupus erythematosus treated with leflunomide.
Topics: Drug Eruptions; Erythema Multiforme; Humans; Leflunomide; Lupus Erythematosus, Systemic | 2020 |
Erythema multiforme-like drug eruption with oral involvement after intake of leflunomide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Eruptions; Erythema Multiforme; | 2003 |
Leflunomide in subacute cutaneous lupus erythematosus - two sides of a coin.
Topics: Adult; Aged; Antirheumatic Agents; Diagnosis, Differential; Drug Eruptions; Enzyme Inhibitors; Eryth | 2008 |
Leflunomide-induced subacute cutaneous lupus erythematosus with erythema multiforme-like lesions.
Topics: Adjuvants, Immunologic; Adult; Antibodies, Antinuclear; Biopsy; Diagnosis, Differential; Erythema Mu | 2008 |