leflunomide has been researched along with Empyema in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Empyema: Presence of pus in a hollow organ or body cavity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is a compound recently shown to reduce T and B cell-mediated responses in a number of experimental rat, mouse, and human systems." | 1.29 | Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine. ( Chong, AS; Clardy, C; Foster, P; McChesney, L; Sankary, H; Williams, JW; Xiao, F, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, JW | 1 |
| Xiao, F | 1 |
| Foster, P | 1 |
| Clardy, C | 1 |
| McChesney, L | 1 |
| Sankary, H | 1 |
| Chong, AS | 1 |
1 other study available for leflunomide and Empyema
| Article | Year |
|---|---|
Leflunomide in experimental transplantation. Control of rejection and alloantibody production, reversal of acute rejection, and interaction with cyclosporine.
Topics: Abdomen; Acute Disease; Animals; Antibody Formation; Cyclosporine; Drug Therapy, Combination; Empyem | 1994 |