leflunomide has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 1 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xuan, J | 1 |
| Ren, Z | 1 |
| Qing, T | 1 |
| Couch, L | 1 |
| Shi, L | 1 |
| Tolleson, WH | 1 |
| Guo, L | 1 |
1 other study available for leflunomide and Electron Transport Chain Deficiencies, Mitochondrial
| Article | Year |
|---|---|
Mitochondrial dysfunction induced by leflunomide and its active metabolite.
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Bongkrekic Acid; Chemical and Drug | 2018 |