leflunomide has been researched along with Edema in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of leflunomide (1a) analogues were examined for antiinflammatory activity using the carrageenan-induced paw edema assay." | 3.72 | Leflunomide analogues as potential antiinflammatory agents. ( Chiu, HF; Huang, WH; Lee, AR; Yang, CL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, WH | 1 |
| Yang, CL | 1 |
| Lee, AR | 1 |
| Chiu, HF | 1 |
| Smith-Oliver, T | 1 |
| Noel, LS | 1 |
| Stimpson, SS | 1 |
| Yarnall, DP | 1 |
| Connolly, KM | 1 |
| Kurtz, ES | 1 |
| Bailey, SC | 1 |
| Arshad, F | 1 |
| Lee, AA | 1 |
| Przekop, PA | 1 |
| Schmidt, K | 1 |
| Bekemeier, H | 1 |
| Giessler, J | 1 |
| Pilopp, H | 1 |
4 other studies available for leflunomide and Edema
| Article | Year |
|---|---|
Leflunomide analogues as potential antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Inflammat | 2003 |
Elevated levels of TNF in the joints of adjuvant arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Assay; Cells, | 1993 |
Leflunomide: an active antiinflammatory and antiproliferative agent in models of dermatologic disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Chronic Disease; | 1995 |
Immunomodulating effects of T-44 in comparison to HWA 486.
Topics: 1-Naphthylamine; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclospor | 1991 |