leflunomide has been researched along with Edema-Proteinuria-Hypertension Gestosis in 2 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Excerpt | Relevance | Reference |
---|---|---|
" Mycophenolate and leflunomide are teratogenic drugs and should be withdrawn before conception in case of programmed pregnancy or should be rapidly discontinued in case of unexpected pregnancy." | 4.91 | Immunosuppression in pregnant women with systemic lupus erythematosus. ( Moroni, G; Ponticelli, C, 2015) |
"Leflunomide is a drug used in rheumatoid arthritis with teratogenic and fetotoxic effects." | 1.35 | A pair of twins born after maternal exposure to leflunomide. ( Heine, K; Poets, CF, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ponticelli, C | 1 |
Moroni, G | 1 |
Heine, K | 1 |
Poets, CF | 1 |
1 review available for leflunomide and Edema-Proteinuria-Hypertension Gestosis
Article | Year |
---|---|
Immunosuppression in pregnant women with systemic lupus erythematosus.
Topics: Contraindications; Cyclosporine; Female; Glucocorticoids; Humans; Hypertension; Immunosuppression Th | 2015 |
1 other study available for leflunomide and Edema-Proteinuria-Hypertension Gestosis
Article | Year |
---|---|
A pair of twins born after maternal exposure to leflunomide.
Topics: Adult; Antirheumatic Agents; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Isoxazoles; | 2008 |