Page last updated: 2024-10-30

leflunomide and Edema-Proteinuria-Hypertension Gestosis

leflunomide has been researched along with Edema-Proteinuria-Hypertension Gestosis in 2 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
" Mycophenolate and leflunomide are teratogenic drugs and should be withdrawn before conception in case of programmed pregnancy or should be rapidly discontinued in case of unexpected pregnancy."4.91Immunosuppression in pregnant women with systemic lupus erythematosus. ( Moroni, G; Ponticelli, C, 2015)
"Leflunomide is a drug used in rheumatoid arthritis with teratogenic and fetotoxic effects."1.35A pair of twins born after maternal exposure to leflunomide. ( Heine, K; Poets, CF, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ponticelli, C1
Moroni, G1
Heine, K1
Poets, CF1

Reviews

1 review available for leflunomide and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Immunosuppression in pregnant women with systemic lupus erythematosus.
    Expert review of clinical immunology, 2015, Volume: 11, Issue:5

    Topics: Contraindications; Cyclosporine; Female; Glucocorticoids; Humans; Hypertension; Immunosuppression Th

2015

Other Studies

1 other study available for leflunomide and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
A pair of twins born after maternal exposure to leflunomide.
    Journal of perinatology : official journal of the California Perinatal Association, 2008, Volume: 28, Issue:12

    Topics: Adult; Antirheumatic Agents; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Isoxazoles;

2008