leflunomide has been researched along with Drug-Induced Stevens Johnson Syndrome in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is an immunomodulating agent with proven efficacy in rheumatoid arthritis." | 7.74 | Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis. ( Baaj, M; El Haouri, M; Hadri, L; Hassikou, H; Safi, S; Tabache, F, 2008) |
| "Leflunomide is an immunomodulating agent with proven efficacy in rheumatoid arthritis." | 3.74 | Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis. ( Baaj, M; El Haouri, M; Hadri, L; Hassikou, H; Safi, S; Tabache, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Wang, F | 1 |
| Li, H | 1 |
| Hao, X | 1 |
| Shen, G | 1 |
| Sun, Y | 1 |
| Xia, J | 1 |
| Hassikou, H | 1 |
| El Haouri, M | 1 |
| Tabache, F | 1 |
| Baaj, M | 1 |
| Safi, S | 1 |
| Hadri, L | 1 |
| Schmutz, JL | 1 |
| Barbaud, A | 1 |
| Tréchot, P | 1 |
| Teraki, Y | 1 |
| Hitomi, K | 1 |
| Sato, Y | 1 |
| Hamamatsu, Y | 1 |
| Izaki, S | 1 |
4 other studies available for leflunomide and Drug-Induced Stevens Johnson Syndrome
| Article | Year |
|---|---|
Toxic Epidermal Necrolysis Induced by Leflunomide in a Patient With Rheumatoid Arthritis.
Topics: Arthritis, Rheumatoid; Humans; Leflunomide; Stevens-Johnson Syndrome | 2021 |
Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis.
Topics: Adjuvants, Immunologic; Adult; Arthritis, Rheumatoid; Cholestyramine Resin; Female; Glucocorticoids; | 2008 |
[Leflunomide and Lyell syndrome].
Topics: Adult; Arthritis, Rheumatoid; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Isoxazoles; L | 2009 |
Leflunomide-induced toxic epidermal necrolysis.
Topics: Adjuvants, Immunologic; Arthritis, Rheumatoid; Female; Humans; Isoxazoles; Leflunomide; Middle Aged; | 2006 |