leflunomide has been researched along with Diseases of Immune System in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Data that were extracted from the medical records included signalment, body weight, underlying indication for leflunomide, dosage of leflunomide, treatment duration, concurrent medications, treatment response, and adverse events." | 1.46 | A Retrospective Study on the Safety and Efficacy of Leflunomide in Dogs. ( Lappin, MR; Legare, M; Sato, M; Veir, JK, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, M | 1 |
| Veir, JK | 1 |
| Legare, M | 1 |
| Lappin, MR | 1 |
| Suzuki, Y | 1 |
| Saito, E | 1 |
| Wakabayashi, T | 1 |
| Suwa, A | 1 |
| Gregory, CR | 1 |
| Stewart, A | 1 |
| Sturges, B | 1 |
| DeManvelle, T | 1 |
| Cannon, A | 1 |
| Ortega, T | 1 |
| Harb, M | 1 |
| Morris, RE | 1 |
1 review available for leflunomide and Diseases of Immune System
| Article | Year |
|---|---|
[Adverse effects of conventional DMARDs and biologic DMARDs].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug | 2007 |
2 other studies available for leflunomide and Diseases of Immune System
| Article | Year |
|---|---|
A Retrospective Study on the Safety and Efficacy of Leflunomide in Dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Immune System Diseases; Immunosuppressive Agents; Isoxazoles; L | 2017 |
Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy.
Topics: Aniline Compounds; Animals; Crotonates; Dog Diseases; Dogs; Female; Hydroxybutyrates; Immune System | 1998 |