leflunomide has been researched along with Diabetes Mellitus in 3 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide is an isoxazol derivative with immunosuppressive capacities in various experimental allo- and xenotransplantation models." | 1.31 | Leflunomide-mediated suppression of antiviral antibody and Tcell responses: differential restoration by uridine. ( Fehr, T; Ochsenbein, AF; Pinschewer, DD; Zinkernagel, RM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kowluru, RA | 1 |
| Alka, K | 1 |
| Guo, Z | 1 |
| Mital, D | 1 |
| Shen, J | 1 |
| Chong, AS | 1 |
| Tian, Y | 1 |
| Foster, P | 1 |
| Sankary, H | 1 |
| McChesney, L | 1 |
| Jensik, SC | 1 |
| Williams, JW | 1 |
| Pinschewer, DD | 1 |
| Ochsenbein, AF | 1 |
| Fehr, T | 1 |
| Zinkernagel, RM | 1 |
3 other studies available for leflunomide and Diabetes Mellitus
| Article | Year |
|---|---|
Mitochondrial Quality Control and Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy.
Topics: Animals; Diabetes Mellitus; Diabetic Retinopathy; DNA, Mitochondrial; Endothelial Cells; Glucose; Hu | 2023 |
Immunosuppression preventing concordant xenogeneic islet graft rejection is not sufficient to prevent recurrence of autoimmune diabetes in nonobese diabetic mice.
Topics: Animals; Autoimmune Diseases; Diabetes Mellitus; Diabetes Mellitus, Experimental; Female; Graft Reje | 1998 |
Leflunomide-mediated suppression of antiviral antibody and Tcell responses: differential restoration by uridine.
Topics: Animals; Antibodies, Viral; Antibody Formation; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Dia | 2001 |