leflunomide has been researched along with Delayed Effects, Prenatal Exposure in 4 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leflunomide (LMF) is an immunemodulatory drug used in the therapy of Rheumatoid Arthritis (RA)." | 8.85 | Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature. ( Banas, T; Batko, B; Górnisiewicz, T; Hajdyla-Banaś, I; Pityńska-Korab, E; Rydz-Stryszowska, I; Skura, A, 2009) |
| "Sixty-four pregnant women with rheumatoid arthritis (RA) who were treated with leflunomide during pregnancy (95." | 7.76 | Birth outcomes in women who have taken leflunomide during pregnancy. ( Braddock, SR; Chambers, CD; Jin, S; Johnson, DL; Jones, KL; Lopez-Jimenez, J; Luo, YJ; Mirrasoul, N; Robinson, LK; Salas, E; Xu, R, 2010) |
| "Leflunomide (LMF) is an immunemodulatory drug used in the therapy of Rheumatoid Arthritis (RA)." | 4.85 | Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature. ( Banas, T; Batko, B; Górnisiewicz, T; Hajdyla-Banaś, I; Pityńska-Korab, E; Rydz-Stryszowska, I; Skura, A, 2009) |
| "Sixty-four pregnant women with rheumatoid arthritis (RA) who were treated with leflunomide during pregnancy (95." | 3.76 | Birth outcomes in women who have taken leflunomide during pregnancy. ( Braddock, SR; Chambers, CD; Jin, S; Johnson, DL; Jones, KL; Lopez-Jimenez, J; Luo, YJ; Mirrasoul, N; Robinson, LK; Salas, E; Xu, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chambers, CD | 1 |
| Johnson, DL | 1 |
| Robinson, LK | 1 |
| Braddock, SR | 1 |
| Xu, R | 1 |
| Lopez-Jimenez, J | 1 |
| Mirrasoul, N | 1 |
| Salas, E | 1 |
| Luo, YJ | 1 |
| Jin, S | 1 |
| Jones, KL | 1 |
| Hajdyla-Banaś, I | 1 |
| Banas, T | 1 |
| Rydz-Stryszowska, I | 1 |
| Batko, B | 1 |
| Skura, A | 1 |
| Górnisiewicz, T | 1 |
| Pityńska-Korab, E | 1 |
| De Santis, M | 1 |
| Straface, G | 1 |
| Cavaliere, A | 1 |
| Carducci, B | 1 |
| Caruso, A | 1 |
| Neville, CE | 1 |
| McNally, J | 1 |
2 reviews available for leflunomide and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Infant | 2009 |
Paternal and maternal exposure to leflunomide: pregnancy and neonatal outcome.
Topics: Female; Humans; Immunosuppressive Agents; Infant, Newborn; Isoxazoles; Leflunomide; Male; Paternal E | 2005 |
2 other studies available for leflunomide and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Birth outcomes in women who have taken leflunomide during pregnancy.
Topics: Adult; Anticholesteremic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Birth Weight; Body Siz | 2010 |
Maternal exposure to leflunomide associated with blindness and cerebral palsy.
Topics: Adult; Antirheumatic Agents; Blindness; Cerebral Palsy; Female; Humans; Infant, Newborn; Isoxazoles; | 2007 |