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leflunomide and Delayed Effects, Prenatal Exposure

leflunomide has been researched along with Delayed Effects, Prenatal Exposure in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Research Excerpts

ExcerptRelevanceReference
"Leflunomide (LMF) is an immunemodulatory drug used in the therapy of Rheumatoid Arthritis (RA)."8.85Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature. ( Banas, T; Batko, B; Górnisiewicz, T; Hajdyla-Banaś, I; Pityńska-Korab, E; Rydz-Stryszowska, I; Skura, A, 2009)
"Sixty-four pregnant women with rheumatoid arthritis (RA) who were treated with leflunomide during pregnancy (95."7.76Birth outcomes in women who have taken leflunomide during pregnancy. ( Braddock, SR; Chambers, CD; Jin, S; Johnson, DL; Jones, KL; Lopez-Jimenez, J; Luo, YJ; Mirrasoul, N; Robinson, LK; Salas, E; Xu, R, 2010)
"Leflunomide (LMF) is an immunemodulatory drug used in the therapy of Rheumatoid Arthritis (RA)."4.85Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature. ( Banas, T; Batko, B; Górnisiewicz, T; Hajdyla-Banaś, I; Pityńska-Korab, E; Rydz-Stryszowska, I; Skura, A, 2009)
"Sixty-four pregnant women with rheumatoid arthritis (RA) who were treated with leflunomide during pregnancy (95."3.76Birth outcomes in women who have taken leflunomide during pregnancy. ( Braddock, SR; Chambers, CD; Jin, S; Johnson, DL; Jones, KL; Lopez-Jimenez, J; Luo, YJ; Mirrasoul, N; Robinson, LK; Salas, E; Xu, R, 2010)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chambers, CD1
Johnson, DL1
Robinson, LK1
Braddock, SR1
Xu, R1
Lopez-Jimenez, J1
Mirrasoul, N1
Salas, E1
Luo, YJ1
Jin, S1
Jones, KL1
Hajdyla-Banaś, I1
Banas, T1
Rydz-Stryszowska, I1
Batko, B1
Skura, A1
Górnisiewicz, T1
Pityńska-Korab, E1
De Santis, M1
Straface, G1
Cavaliere, A1
Carducci, B1
Caruso, A1
Neville, CE1
McNally, J1

Reviews

2 reviews available for leflunomide and Delayed Effects, Prenatal Exposure

ArticleYear
Pregnancy course and neonatal outcome after exposure to leflunomide--2 cases report and review of literature.
    Przeglad lekarski, 2009, Volume: 66, Issue:12

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Infant

2009
Paternal and maternal exposure to leflunomide: pregnancy and neonatal outcome.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:7

    Topics: Female; Humans; Immunosuppressive Agents; Infant, Newborn; Isoxazoles; Leflunomide; Male; Paternal E

2005

Other Studies

2 other studies available for leflunomide and Delayed Effects, Prenatal Exposure

ArticleYear
Birth outcomes in women who have taken leflunomide during pregnancy.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:5

    Topics: Adult; Anticholesteremic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Birth Weight; Body Siz

2010
Maternal exposure to leflunomide associated with blindness and cerebral palsy.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:9

    Topics: Adult; Antirheumatic Agents; Blindness; Cerebral Palsy; Female; Humans; Infant, Newborn; Isoxazoles;

2007