Page last updated: 2024-10-30

leflunomide and Cytomegalovirus Retinitis

leflunomide has been researched along with Cytomegalovirus Retinitis in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Cytomegalovirus Retinitis: Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in AIDS patients and can cause blindness.

Research Excerpts

ExcerptRelevanceReference
"To describe leflunomide use in the treatment of drug resistant cytomegalovirus retinitis."7.85Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( Goldstein, DA; Jumroendararasame, C; Minkus, CL; Pursell, K; Rifkin, LM, 2017)
"Leflunomide is a novel drug with both immunosuppressive and anti-CMV properties."5.33Treatment of multidrug-resistant cytomegalovirus retinitis with systemically administered leflunomide. ( Chan, LK; Levi, ME; Mandava, N; Olson, JL; Weinberg, A, 2006)
"To describe leflunomide use in the treatment of drug resistant cytomegalovirus retinitis."3.85Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( Goldstein, DA; Jumroendararasame, C; Minkus, CL; Pursell, K; Rifkin, LM, 2017)
"Leflunomide is a novel drug with both immunosuppressive and anti-CMV properties."1.33Treatment of multidrug-resistant cytomegalovirus retinitis with systemically administered leflunomide. ( Chan, LK; Levi, ME; Mandava, N; Olson, JL; Weinberg, A, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Fu, L1
Santhanakrishnan, K1
Al-Aloul, M1
Jones, NP1
Steeples, LR1
Dunn, JH1
Weinberg, A2
Chan, LK2
Mandava, N2
Levi, ME2
Olson, JL2
Rifkin, LM1
Minkus, CL1
Pursell, K1
Jumroendararasame, C1
Goldstein, DA1

Reviews

1 review available for leflunomide and Cytomegalovirus Retinitis

ArticleYear
Management of Ganciclovir Resistant Cytomegalovirus Retinitis in a Solid Organ Transplant Recipient: A Review of Current Evidence and Treatment Approaches.
    Ocular immunology and inflammation, 2020, Oct-02, Volume: 28, Issue:7

    Topics: Antiviral Agents; Cytomegalovirus Retinitis; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans;

2020

Other Studies

3 other studies available for leflunomide and Cytomegalovirus Retinitis

ArticleYear
Long-term suppression of multidrug-resistant cytomegalovirus retinitis with systemically administered leflunomide.
    JAMA ophthalmology, 2013, Volume: 131, Issue:7

    Topics: Administration, Oral; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resi

2013
Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis.
    Ocular immunology and inflammation, 2017, Volume: 25, Issue:1

    Topics: Administration, Oral; Aged; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resis

2017
Treatment of multidrug-resistant cytomegalovirus retinitis with systemically administered leflunomide.
    Transplant infectious disease : an official journal of the Transplantation Society, 2006, Volume: 8, Issue:1

    Topics: Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Retinitis; Drug Resistance, Multiple, Vira

2006