Page last updated: 2024-10-30

leflunomide and Coronavirus Infections

leflunomide has been researched along with Coronavirus Infections in 4 studies

Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.

Coronavirus Infections: Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE).

Research Excerpts

ExcerptRelevanceReference
"Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA)."5.05A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab. ( Cai, S; Dong, L; Li, M; Sun, W, 2020)
"A case with rheumatoid arthritis and insufficient compensation under disease-modifying combined long-term therapy with methotrexate and leflunomide is reported."3.96[Biological therapy after COVID-19 infection : No reactivation of a COVID-19 infection with positive SARS-CoV-2 antibody status under biological therapy]. ( Lange, U; Müller-Ladner, U; Steinchen, N, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Steinchen, N1
Müller-Ladner, U1
Lange, U1
Cai, S1
Sun, W1
Li, M1
Dong, L1
Coelho, AR1
Oliveira, PJ1
Xiong, R1
Zhang, L1
Li, S1
Sun, Y1
Ding, M1
Wang, Y1
Zhao, Y1
Wu, Y1
Shang, W1
Jiang, X1
Shan, J1
Shen, Z1
Tong, Y1
Xu, L1
Chen, Y1
Liu, Y1
Zou, G1
Lavillete, D1
Zhao, Z1
Wang, R1
Zhu, L1
Xiao, G1
Lan, K1
Li, H1
Xu, K1

Reviews

1 review available for leflunomide and Coronavirus Infections

ArticleYear
A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab.
    Clinical rheumatology, 2020, Volume: 39, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Antirheumatic Agents; Antiviral Agents; Arthritis, R

2020

Other Studies

3 other studies available for leflunomide and Coronavirus Infections

ArticleYear
[Biological therapy after COVID-19 infection : No reactivation of a COVID-19 infection with positive SARS-CoV-2 antibody status under biological therapy].
    Zeitschrift fur Rheumatologie, 2020, Volume: 79, Issue:6

    Topics: Antibodies, Viral; Arthritis, Rheumatoid; Betacoronavirus; Biological Therapy; Coronavirus Infection

2020
Dihydroorotate dehydrogenase inhibitors in SARS-CoV-2 infection.
    European journal of clinical investigation, 2020, Volume: 50, Issue:10

    Topics: Antiviral Agents; Betacoronavirus; Biphenyl Compounds; Coronavirus Infections; COVID-19; COVID-19 Dr

2020
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2.
    Protein & cell, 2020, Volume: 11, Issue:10

    Topics: Animals; Antiviral Agents; Betacoronavirus; Binding Sites; Cell Line; Coronavirus Infections; COVID-

2020