leflunomide has been researched along with Complication, Postoperative in 10 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Excerpt | Relevance | Reference |
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" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance." | 7.85 | Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017) |
"Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 5.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
" We describe a case of a cytomegalovirus (CMV)-seronegative kidney transplant recipient from a CMV-seropositive donor, whose course was complicated during valganciclovir prophylaxis by CMV disease, ultimately progressing to ganciclovir, foscarnet, and cidofovir resistance." | 3.85 | Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. ( Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L, 2017) |
"Leflunomide treatment for CMV disease in renal transplant recipients is effective, simple, and economical." | 2.71 | A prospective evaluation of leflunomide therapy for cytomegalovirus disease in renal transplant recipients. ( Balakrishnan, N; Chandy, S; Chandy, SJ; Fleming, DH; Jacob, CK; John, GT; Kirubakaran, MG; Krishnamurthy, K; Manivannan, J; Peter, S, 2005) |
" The dosage and time of therapy need to be explored in the future; additional studies of large samples are needed." | 1.42 | BK Virus-Associated Nephropathy with Plasma Cell-Rich Infiltrates Treated by Bortezomib-Based Regimen. ( Chen, JS; Cheng, DR; Ji, SM; Li, X; Liu, ZH; Wen, JQ; Wu, D; Xie, KN; Zhang, MC, 2015) |
"Leflunomide was selected as a last resort to avoid the nephrotoxicity of cidofovir." | 1.34 | Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. ( Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (10.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 4 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Echenique, IA | 1 |
Beltran, D | 1 |
Ramirez-Ruiz, L | 1 |
Najafian, N | 1 |
Agrawal, N | 1 |
Velázquez Benito, A | 1 |
Bellosta Diago, E | 1 |
Santos Lasaosa, S | 1 |
Pascual Millán, LF | 1 |
Wu, D | 1 |
Zhang, MC | 1 |
Chen, JS | 1 |
Li, X | 1 |
Cheng, DR | 1 |
Xie, KN | 1 |
Ji, SM | 1 |
Liu, ZH | 1 |
Wen, JQ | 1 |
Jung, YH | 1 |
Moon, KC | 1 |
Ha, JW | 1 |
Kim, SJ | 1 |
Ha, IS | 1 |
Cheong, HI | 1 |
Kang, HG | 1 |
John, GT | 1 |
Manivannan, J | 1 |
Chandy, S | 1 |
Peter, S | 1 |
Fleming, DH | 1 |
Chandy, SJ | 1 |
Balakrishnan, N | 1 |
Krishnamurthy, K | 1 |
Kirubakaran, MG | 1 |
Jacob, CK | 1 |
Josephson, MA | 1 |
Javaid, B | 1 |
Kadambi, PV | 1 |
Meehan, SM | 1 |
Williams, JW | 1 |
Fuerst, M | 1 |
Möhl, H | 1 |
Baumgärtel, K | 1 |
Rüther, W | 1 |
Duclos, AJ | 1 |
Krishnamurthi, V | 1 |
Lard, M | 1 |
Poggio, E | 1 |
Kleeman, M | 1 |
Winans, C | 1 |
Fatica, R | 1 |
Nurko, S | 1 |
Battiwalla, M | 1 |
Paplham, P | 1 |
Almyroudis, NG | 1 |
McCarthy, A | 1 |
Abdelhalim, A | 1 |
Elefante, A | 1 |
Smith, P | 1 |
Becker, J | 1 |
McCarthy, PL | 1 |
Segal, BH | 1 |
Gregory, CR | 1 |
3 reviews available for leflunomide and Complication, Postoperative
Article | Year |
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Leflunomide therapy for BK virus allograft nephropathy after pediatric kidney transplantation.
Topics: Antiviral Agents; BK Virus; Child; Female; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantati | 2013 |
Leflunomide in solid organ transplantation and polyoma virus infection.
Topics: Antiviral Agents; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Organ Transplantation; | 2006 |
Immunosuppressive approaches to the prevention of graft vascular disease.
Topics: Coronary Disease; Cyclosporine; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase I | 1998 |
1 trial available for leflunomide and Complication, Postoperative
Article | Year |
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A prospective evaluation of leflunomide therapy for cytomegalovirus disease in renal transplant recipients.
Topics: Adult; Antiviral Agents; Cytomegalovirus Infections; Female; Humans; Isoxazoles; Kidney Transplantat | 2005 |
6 other studies available for leflunomide and Complication, Postoperative
Article | Year |
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Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Respo | 2017 |
[Acute sensory-motor axonal neuropathy (Guillain-Barre syndrome) following vertebroplasty].
Topics: Accidental Falls; Arthritis, Rheumatoid; Female; Guillain-Barre Syndrome; Humans; Immunocompromised | 2014 |
BK Virus-Associated Nephropathy with Plasma Cell-Rich Infiltrates Treated by Bortezomib-Based Regimen.
Topics: Adult; Antineoplastic Agents; BK Virus; Bortezomib; Female; Humans; Isoxazoles; Kidney Diseases; Kid | 2015 |
Leflunomide increases the risk of early healing complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Combined Modality Thera | 2006 |
Prevalence and clinical course of BK virus nephropathy in pancreas after kidney transplant patients.
Topics: Antiviral Agents; BK Virus; Drug Therapy, Combination; Humans; Immunosuppression Therapy; Isoxazoles | 2006 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Co | 2007 |