leflunomide has been researched along with Colitis in 5 studies
Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide." | 7.73 | Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005) |
| "Diarrhoea and weight loss are frequently reported adverse events in rheumatoid arthritis (RA) patients receiving the disease-modifying antirheumatic drug (DMARD) leflunomide." | 3.73 | Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide. ( Vandooren, AK; Verschueren, P; Westhovens, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lui, J | 1 |
| de la Fuente, J | 1 |
| Halland, M | 1 |
| Muhammad, T | 1 |
| Zafar, M | 1 |
| Quiroga, J | 1 |
| Whitehead, M | 1 |
| Kwok, AMF | 1 |
| Morosin, T | 1 |
| Verschueren, P | 1 |
| Vandooren, AK | 1 |
| Westhovens, R | 1 |
| Finn, S | 1 |
| Bond, J | 1 |
| McCarthy, D | 1 |
| Sheahan, K | 1 |
| Quinn, C | 1 |
5 other studies available for leflunomide and Colitis
| Article | Year |
|---|---|
Colitis in a Rheumatologic Patient.
Topics: Antirheumatic Agents; Arthritis, Psoriatic; Biopsy; Colitis; Colon; Colonoscopy; Female; Humans; Int | 2020 |
Leflunomide-induced delayed onset colitis.
Topics: Arthritis, Rheumatoid; Colitis; Humans; Immunosuppressive Agents; Leflunomide | 2021 |
Leflunomide-induced colitis in association with enterocutaneous fistula in an immunosuppressed patient with renal transplant and rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Colitis; Diarrhea; Humans; Immunocompromised Host; Immunosuppressive Ag | 2019 |
Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Colitis; Colon; Colon | 2005 |
Angioinvasive aspergillosis presenting as neutropenic colitis.
Topics: Adalimumab; Adjuvants, Immunologic; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodi | 2006 |